Summary
Three cases of systemic reaction to bone cement are reported. Two patients had a cardiac arrest immediately after insertion of the cement during total hip replacement. The third patient had bilateral total hip replacement, the second procedure being done six weeks after the first. On each occasion the patient developed unexplained pyrexia and it is suggested that this might be due to allergy.
The chemistry of bone cement is discussed and it is suggested that absorbed monomer may be responsible for systemic reactions to the cement.
Similar content being viewed by others
References
Bloch, B., Haken, J. K., Hastings, G. W. 1970. Evaluation of cold-curing acrylic cement for prosthesis stabilization. Clinical orthopaedics, 72, 239.
Charnley, J. 1970a. Acrylic cement in orthopaedic surgery. Firsh Edition, Edinburgh, Livingstone, p. 34.
Charnley, J. 1970b. Acrylic cement in orthopaedic surgery. First Edition, Edinburgh, Livingstone, p. 76.
Charnley, J. 1970c. Acrylic cement in orthopaedic surgery. First Edition, Edinburgh, Livingstone, p. 75, 76.
Charnley, J. 1970d. Acrylic cement in orthopaedic surgery. First Edition, Edinburgh, Livingstone, p. 75, 76.
Fisher, A. A. 1956. Allergic sensitisation of the skin and oral mucosa to acrylic resin dental material. Journal of Prosthetic Dentistry, 6, 593.
Frost, P. M. 1970. Correspondence. Brit. med. J., iii, 524.
Homsy, C. A., Tullos, H. S., King, J. W. 1969. Evaluation of rapid-cure acrylic cement for prosthesis stabilisation. Clinical orthopaedics and related research, 67, 169.
Lazansky, M. G. 1970. Complications in total hip replacement with the Charnley technique. Clinical Orthopaedics, 72, 40.
Nquist, G. 1958. Sensitivity to methylmethacrylate. Transactions of the royal schools of dentistry. Stockholm ann Umea No. 1, series 2, 1, 35.
Powell, J. N., McGrath, P. J., Lahiri, S. K., Hill, P. 1970. Cardiac arrest associated with bone cement. Brit. med. J., iii, 326.
Spealman, C. R., Main, R. J., Haag, H. B., Larson, P. S. 1945. Monomeric methylmethacrylate; Studies on toxicity. Industrial Medicine, 14, 292.
Thomas, T. A., Sutherland, I. C, Waterhouse, T. D. 1971. Cold curing acrylic cement. Anaesthesia, 26, 298.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kirwan, W.O. Systemic phenomena and bone cement. Ir J Med Sci 142, 342–345 (1973). https://doi.org/10.1007/BF02950031
Issue Date:
DOI: https://doi.org/10.1007/BF02950031