The response to cold of the blood vessels of denervated fincers during the receneration of the nerves

  • J. T. Shepherd
  • I. D. Thompson


1. The vascular response to cold in the finger tip has been determined in seven subjects at varying intervals after peripheral nerve section.

2. A close correlation has been found between the degree of sensory return and the improvement in the cold vasodilatation.

3. No improvement in cold response was found in the two cases in whom there was no return of sensation.

4. These findings are compatible with the view that the improvement in the cold vasodilatation depends upon the regeneration of local axon reflex pathways.


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  1. Gibbon, J. E. and Landis, E. M. (1932).J. Clin. Invest., 11, 1019.PubMedCentralPubMedCrossRefGoogle Scholar
  2. Greenfield, A. D. M. and Shepherd, J. T. (1950).Clin. Sci., 9, 323.PubMedGoogle Scholar
  3. Greenfield, A. D. M., Shepherd, J. T. and Whelan, R. F. (1951).Clin. Sci., 10, 347PubMedGoogle Scholar
  4. Lewis, T. (1930).Heart, 15, 177.Google Scholar
  5. Lewis, T. and Pickering, G. W. (1936).Clin. Sci., 2, 149.Google Scholar
  6. Thompson, I. D. (1952). M.D. Thesis, Queen’s University, Belfast. (Available for consultation in the Library of Queen’s University, Belfast).Google Scholar

Copyright information

© Springer 1953

Authors and Affiliations

  • J. T. Shepherd
    • 1
  • I. D. Thompson
    • 1
  1. 1.From the Department of PhysiologyThe Queen’s University of BelfastIreland

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