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Irish Journal of Medical Science

, Volume 166, Issue 4, pp 239–240 | Cite as

Carbimazole induced agranulocytosis: Rescue with human recombinant Granulocyte Colony Stimulating factor

  • J. A. O’Hare
  • T. Azher
Article

Summary

We report on a 25 yr old woman with primary autoimmune hyperthyroidism who was treated with carbimazole. Forty-three days later she developed agranulocytosis (64 × 106/l). With 4 days treatment with recombinant human Granulocyte Colony Stimulating factor the granulocyte count rose to normal — 4,350 cells X 106/l. This is considerably faster than the rate of spontaneous recovery which usually takes one to 2 weeks.

Keywords

Agranulocytosis Leucocyte Count Infectious Mononucleosis Methimazole Carbimazole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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Copyright information

© Springer 1997

Authors and Affiliations

  • J. A. O’Hare
    • 1
    • 2
  • T. Azher
    • 1
    • 2
  1. 1.Department of MedicineLimerick Regional General HospitalIreland
  2. 2.University College CorkIreland

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