Pulmonary alveolar proteinosis: Primary and secondary, a report of three cases
Three cases of the rare disorder pulmonary alveolar proteinosis (PAP) presented to our unit over the past thirteen years. Two of the patients conformed to the classical description of idiopathic or “primary” PAP. One patient appeared to have co-existing extrinsic allergic alveolitis with “secondary” PAP, an association not previously described. This patient has required continued steroid therapy, a mode of treatment usually contraindicated in PAP.
KeywordsInterstitial Lung Disease Pulmonary Alveolar Proteinosis Lung Lavage Transbronchial Biopsy Open Lung Biopsy
- 1.Rosen, S. H., Castleman, B., Liebow, A. A. Pulmonary alveolar proteinosis. N. Eng. J. Med. 1958: 258, 1123–42.Google Scholar
- 4.Scully, R. E., Mark, E. J., McNeely, B.U. Case Records of the Massachusetts General Hospital Weekly Clinicopthological exercises, Case 14. N. Eng, J. Med. 1984: 310, 906–16.Google Scholar
- 10.Leatherman, J. W., Michael, A. F., Schwartz, B. A., Hoidal, J. R. Lung T cells in hypersensitivity pneumonitis, Ann. Intern Med. 1984: 100, 390–92.Google Scholar
- 13.Green, D., Criner, G. J. Twenty-five year follow-up of a patient treated with lung lavage for pulmonary proteinosis. N. Eng. J. Med. 1987: 317, 839–40.Google Scholar