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Cholesterol levels in normal Irish adults: The mater hospital cholesterol screening survey

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Abstract

Serum samples from 954 Irish adults (604 males, 350 females) aged 18 to 65 years were analyzed within 24 hours of receipt for non-fasting total serum cholesterol levels. The subjects were volunteer blood donors (Blood Transfusion Service Board, Pelican House, Dublin) presenting from June 1990 to February 1991.

Serum cholesterol increased significantly with age in both males and females. Mean serum cholesterol in males increased from 4.5 (± 0.9) mmol/l in those < 25 years, to 5.7 (± 1.0) mmol/l at age 55-64 years. In females, mean serum cholesterol increased from 4.3 (± 0.9) mmol/l less than 25 years to 6.2 (±0.8) mmol/l at age 55-64 years. Options for reporting cholesterol ranges are discussed. The overall mean cholesterol concentration of 5.1 mmol/l seen in this study is lower than that reported for comparable studies of U.K. and American subjects, but higher than observed in Japanese individuals. Almost 48% of the studied population had a serum cholesterol value less than 5 mmol/1 and over 56% had levels less than 5.2 mmol/l.

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References

  1. Dawber, T. R., Moore, F. E., Mann, G. V. Coronary heart disease in the Framingham Study. Am. J. Pub. Health 1957; 47: 4–24.

    PubMed  CAS  Google Scholar 

  2. Current status of blood cholesterol measurement in clinical laboratories in the United States: A report from the laboratory standardization panel of the National Cholesterol Education Program. Clin. Chem. 1988; 34: 193–201.

  3. World Health Statistics Annual, 1993. WHO Official Publication, Geneva, Switzerland 1994.

  4. Shelley, E., Daly, L., Kilcoyne, D., Graham, I., Mulcahy, R. Risk factors for coronary heart disease: A population survey in County Kilkenny, Ireland, in 1985. Ir. J. Med. Sci. 1991; 160(Suppl9):22–8.

    Article  PubMed  Google Scholar 

  5. SAS User’s Guide Version SAS Institute Inc. Cary NC. USA.

  6. Whitehead, T. P., Robinson, D., Hale, A. C., Bailey, A. R. Clinical Chemistry and Haematology: Adult Reference Values. BUPA Medical Research and Development Ltd., London, U.K.

  7. Grundy, S. M., Vega, G. L. Causes of high blood cholesterol. Research Advance Series. Circ. 1990; 91: 412–24.

    Google Scholar 

  8. Tunstall-Pedoe, H., Smith, W. C. S., Tavensdale, R. How-often-that-high graphs of serum cholesterol. Lancet 1989; i: 540–2.

    Article  Google Scholar 

  9. Asui, T. A concept for normal range of serum cholesterol. Rinsho-Byori. 1991; 39: 483–8.

    Google Scholar 

  10. Fong, P., Tarn, S. C., Tai, Y., Lau, C., Lee, J., Sha, Y. Serum lipid and apolipoprotein distributions in Hong Kong Chinese. J. Epid. Comm. Health 1994; 48: 155–9.

    Article  Google Scholar 

  11. Hemel, J. B., Hindriks, F. R., van der Slik, W. Critical discussion on a method for derivation of reference limits in clinical chemistry from a patient population. J. Auto. Chem. 1985; 7: 20–30.

    CAS  Google Scholar 

  12. Graham, I. The management of hyperlipidaemia. Ir. J. Med. Sci. 1993; 86: 40–1.

    CAS  Google Scholar 

  13. Pocock, S. J., Seed, P. T. Cholesterol in elderly-womenLancet. 1992; 339: 1426.

    Article  PubMed  CAS  Google Scholar 

  14. Sporik, R., Johnstone, J. H., Cogswell, J. J. The longitudinal study of cholesterol values in 68 children from birth to 11 years of age. Arch. Dis. Child. 1991; 66: 134–137.

    PubMed  CAS  Google Scholar 

  15. Godsland, I. Intra-individual variation: significant changes in parameters of lipid and carbohydrate metabolism in the individual and intra-individual variation in different test populations. Ann. Clin. Biochem. 1985; 22: 618–24.

    PubMed  Google Scholar 

  16. Stavljenic, J., Sertic, J., Kumar, K., Vrkic, N., Fumic, K. Analytical Performance of the Abbott Spectrum High-Performance Diagnostic System Evaluated. Clin. Chem. 1988; 34: 1917.

    PubMed  CAS  Google Scholar 

  17. Segal, P., Bachorik, P. S., Rifkind, B. M., Levy, R. I. Lipids and dyslipoproteinemia: Clinical Diagnosis and Management by Laboratory Methods. J. B. Henry, 17th Edition W. B. Saunders Company, Sussex, U.K. 1984.

    Google Scholar 

  18. Kroll, M. H., Ruddell, M., Elin, R. E. Analytical biasfor cholesterol and the percent of the population deemed at risk for coronary heart disease. Clin. Chem. 1988; 34: 2009–11.

    PubMed  CAS  Google Scholar 

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Collier, J.F., Maguire, S., McGing, P. et al. Cholesterol levels in normal Irish adults: The mater hospital cholesterol screening survey. I.J.M.S. 165, 177–181 (1996). https://doi.org/10.1007/BF02940246

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