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Irish Journal of Medical Science

, Volume 151, Issue 1, pp 1–5 | Cite as

Evaluation of follow-up methods to detect relapse after mastectomy in breast cancer patients

  • B. Cantwell
  • J. J. Fennelly
  • M. Jones
Article

Summary

ARETROSPECTIVE assessment of follow-up methods after mastectomy for operable breast cancer was carried out in 84 patients. Forty-two patients have had recurrence of breast cancer, one patient developed a second primary and 41 patients remain free of disease. Patient symptomatology gave first evidence in 24 (57.1%) patients who relapsed. Physical examination in asymptomatic patients gave first evidence of relapse in 12 patients (28.5%). Serial measurements of carcinoembryonic antigen, alkaline phosphatase and erythrocyte sedimentation rate during the disease-free interval were more commonly abnormal in the patients who suffered a relapse than in those who remained disease free. In the recurrence group 14 of 18 patients (77.7%) had at least one blood test abnormal during the disease-free interval compared to 14 of 36 (38.8%) of patients who remained disease free, x2 = 7.27, D.F. = I, p<0.01. Isotopie bone scans and chest x-rays (C.X.R.s) at approximately yearly intervals detected only 11.9% and 2.3% of patients with relapse respectively in the absence of abnormal clinical features or blood tests.

Keywords

Breast Cancer Breast Cancer Patient Bone Metastasis Operable Breast Cancer Recurrence Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 1982

Authors and Affiliations

  • B. Cantwell
    • 1
  • J. J. Fennelly
    • 1
  • M. Jones
    • 1
  1. 1.Department of Medical OncologySt. Vincent’s HospitalDublinIreland

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