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Haemoglobin solution as an oxygen-carrying resuscitation fluid in haemorrhagic shock

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Summary

A SOLUTION of pyridoxalated haemoglobin has been prepared and tested in an animal shock model by comparing its efficiency in resuscitating an animal from hypovolaemic shock with dextran. It is as efficient as dextran in restoring blood pressure, and makes more oxygen available to the tissues. Great care must be exercised in the preparation of the haemoglobin solution.

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Authors and Affiliations

  1. Departments of Surgery and Haemotology, The Queen’s University of Belfast, Ireland

    William Odling-Smee & Conor McLarnon

Authors
  1. William Odling-Smee
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  2. Conor McLarnon
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Additional information

We are especially grateful to Dr. T. J. Lapp in for his help and advice on this work, and to Mr. G. Creighton and the staff of the Medeical Research Unit, Queen’s University of Belfast.

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Odling-Smee, W., McLarnon, C. Haemoglobin solution as an oxygen-carrying resuscitation fluid in haemorrhagic shock. I.J.M.S. 153, 385–388 (1984). https://doi.org/10.1007/BF02939801

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  • DOI: https://doi.org/10.1007/BF02939801

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