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HLA identity in juvenile onset diabetes

  • G. A. FitzGerald
  • M. I. Drury
Article

Summary

Hla typing at the A and B locus was performed in 13 sibships of juvenile onset diabetics (JOD). Eight families had more than one diabetic sibling. HLA identity was significantly associated with the development of JOD. Fifty-five per cent of the HLA identical index siblings were diabetic. HLA-B8 was significantly increased in the diabetic sibs. There was a significant increase in HLA-A28 and decrease in HLA-B17 in the non-diabetic siblings compared with controls.

Keywords

Juvenile Onset Diabetes Islet Cell Antibody Juvenile Onset Mater Misericordiae Hospital Juvenile Onset Diabetes Mellitus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • G. A. FitzGerald
    • 1
  • M. I. Drury
    • 1
  1. 1.Department of Diabetes and EndocrinologyMater Misericordiae HospitalDublin 7

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