Antibiotic resistance of faecal coliforms in hospital and city sewage in Galway
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The incidence of antibiotic resistance and of R-factors in the faecal coliform populations of raw hospital and city sewage was investigated in Galway city. During a 14-month sampling period, the incidence of faecal coliform resistance to ampicillin, tetracycline, chloramphenicol and streptomycin in city sewage was on a par with, and in some cases, greater than the incidence in hospital sewage. Over 90% of resistantE. coli isolates from hospital and city sewage were simultaneously resistant to two or more antibiotics. In the majority of isolates, resistance was R-factor carried, with 90% of the city sewage isolates and 69% of the hospital sewage strains capable of conjugal transfer to a sensitiveE. coli recipient. The data indicates the presence of an undesirably high level of transferable antibiotic resistance in the gut flora of the healthy non-hospitalized population in Galway.
KeywordsAntibiotic Resistance Faecal Coliform Domestic Sewage Resistance Determinant City Sewage
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- Datta, N. 1969. Drug resistance and R-factors in the bowel bacteria of London patients before and after admission to hospital. Br. med. J. ii, 407–411.Google Scholar
- Lebek, G. 1972. Epidemiological investigations of R-factors in man and animals in Switzerland.In “Bacterial Plasmids and Antibiotic Resistance” (Eds. V. Kremery, L. Rosival and T. Watanabe), pp. 47–55, Springer Verlag, Berlin.Google Scholar
- Linton, K. B., Richmond, M. H., Bevan, R. and Gillespie, W. A. (1972b). Antibiotic resistance and R-factors in coliform bacilli isolated from hospital and domestic sewage. J. Med. Microbiol. 7, 91–103.Google Scholar
- Mercer, H. B., Pocurull, D., Gaines, S., Wilson, W. and Bennett, J. V. 1971. Characteristics of antimicrobial resistance ofEscherichia coli from animals: relationship to veterinary and management uses of antimicrobial agents. Appl. Microbial. 22, 700–705.Google Scholar
- Monaghan, C. 1980. Epidemiology of R-factor resistance inEscherichia coli Ph.D. Thesis, National University of Ireland, Dublin.Google Scholar
- Peer, A. K. 1978. Antibiotic resistance inE. coli of human and animal origin in the Galway area. M. Sc. Thesis, N.U.I.Google Scholar
- Richmond, M. H. and Linton, K. B. 1980. The use of tetracycline in the community and its possible relation to the excretion of tetracycline-resistant bacteria. J. Antimicrob. Chemotherap. 33–41.Google Scholar
- Wells, D. M. and James, O. B. 1973. Transmission of infectious drug resistance from animals to man. J. Hyg. 71, 209–215.Google Scholar
- Wiedemann B., Knothe, H. and Holzer, P. 1969. A study of the distribution of R-factors. Zentbl. Bakt. Parasitkde. 1 Abt. Orig. 212, 97.Google Scholar