Epidemiology of hepatitis E virus in male blood donors in Jeddah, Saudi Arabia

  • M. Abdelaal
  • T. H. Zawawi
  • E. al Sobhi
  • O. Jeje
  • C. Gilpin
  • A. Kinsara
  • A. Osoba
  • G. A. Oni


To our knowledge, only a few epidemiological reports on the prevalence of hepatitis E antibodies in Saudi blood donors have been published.

Men of several nationalities, donating blood at King Khalid National Guard Hospital (Jeddah, Saudi Arabia) were selected (n = 593) for this study examining the seroprevalence of hepatitis E virus (HEV) in the local male donor population and testing the relationship of the antibody to HEV (anti-HEV) to donor characteristics using Odds Ratio (OR) and Chi-square statistic.

The prevalence of anti-HEV in the group examined was 16.9 per cent (100/593). The seroprevalence for Saudi donors was 14.8 per cent compared with 33.3 per cent for non-Saudis of Middle Eastern origin. Donors who were 40 yr and over had significantly higher seroprevalence than those donors who were 30 yr or younger (OR =2.5, p = 0.006). There was a significant association between anti-HEV and anti-HCV with donors who were positive to anti-HCV having about 5 times the risk of HEV than those who were anti-HCV negative (p = 0.02).

These findings demonstrate the high seroprevalence rate of anti-HEV among male blood donors in Saudi Arabia.


Blood Donor Donor Characteristic Male Blood Donor Middle Eastern Origin High Seroprevalence Rate 
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Copyright information

© Springer-Verlag 1998

Authors and Affiliations

  • M. Abdelaal
    • 1
  • T. H. Zawawi
    • 2
  • E. al Sobhi
    • 1
  • O. Jeje
    • 1
  • C. Gilpin
    • 1
  • A. Kinsara
    • 2
  • A. Osoba
    • 1
  • G. A. Oni
    • 2
  1. 1.Departments of PathologyKing Khalid National Guard HospitalSaudi Arabia
  2. 2.Departments of MedicineKing Khalid National Guard HospitalSaudi Arabia

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