The clinical use of antibiotics
In this short paper I have concentrated on a simpleclinical approach to the rational use of antibacterial agents. In stressing this bedside method, what I will call microbial thinking, I have excluded the difficulties of drug resistance, combined therapy, hypersensitivity and the constraints imposed by concomitant disease—particularly renal insufficiency. I have said nothing of the role of the microbiologist—essential for full understanding of problems in chemotherapy and whose collaboration is crucial. This restricted approach may have produced some distortion or even oversimplification of what is admittedly often an extremely complex situation, but I hope that the single-minded simplicity of the message may compensate for these deficiencies.
KeywordsBlood Culture Typhoid Fever Sulphonamide IRISH Journal Bacillus Anthracis
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