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An unusual case of pulmonary hypertension in a young male

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References

  1. Simonneau G, Galie N, Rubin LJ, et al. Clinical classification of pulmonary hypertension.J Am Coll Cardiol 2004; 43 (Suppl S): 5S-12S.

    Article  PubMed  Google Scholar 

  2. Craig RJ, Selzer A. Natural history and prognosis of atrial spetal defect.Circulation 1968; 37: 805–15.

    PubMed  CAS  Google Scholar 

  3. Gaine SP, Rubin LJ. Primary pulmonary hypertension.Lancet 1998; 352: 719–25.

    Article  PubMed  CAS  Google Scholar 

  4. Rubin LJ. Primary pulmonary hypertension.N Engl J Med 1997; 336: 111–7.

    Article  PubMed  CAS  Google Scholar 

  5. Durie B, Salmon S. A clinical staging system for multiple myeloma.Cancer 1975; 36: 842–7.

    Article  PubMed  CAS  Google Scholar 

  6. Pope B, Brown R, Gibson J, Joshua D. The bone marrow plasma cell labeling index by flow-cytometry.Cytometry 1999; 38: 286–92.

    Article  PubMed  CAS  Google Scholar 

  7. Fedullo PF, Auger WR, Kerr KM, Rubin LJ. Chronic thromboembolic pulmonary hypertension.N Engl J Med 2001; 345: 1465–72.

    Article  PubMed  CAS  Google Scholar 

  8. Lang IM. Chronic thromboembolic pulmonary hypertension-not so rare after all,N Engl J Med 2004; 350: 2236–8.

    Article  PubMed  CAS  Google Scholar 

  9. Zangari M, Saghafifar F, Anaisse E, et al. Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications.Blood Coagul Fibrinolysis 2002; 13: 187–92.

    Article  PubMed  CAS  Google Scholar 

  10. Zangari M, Saghafifar F, Mehta P, Barlogie B, Fink L, Tricot G. The blood coagulation mechanism in multiple myeloma.Semin Thromb Hemost 2003; 29: 275–82.

    Article  PubMed  CAS  Google Scholar 

  11. Galie N, Torbicki A, Barst R, et al. Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology.Eur Heart J 2004; 25: 2243–78.

    Article  PubMed  Google Scholar 

  12. Dispenzieri A, Kyle RA, Lacy MQ, et al. POEMS syndrome: definitions and long-term outcome.Blood 2003; 101: 2496–506.

    Article  PubMed  CAS  Google Scholar 

  13. Ribadeau-Dumas S, Tillie-Leblond I, Rose C, et al. Pulmonary hypertension associated with POEMS syndrome.Eur Respir J 1996; 9: 1760–2.

    Article  PubMed  CAS  Google Scholar 

  14. Rose C, Zandecki M, Copin MC, et al. POEMS syndrome: report on six patients with unusual clinical signs, elevated levels of cytokines, macrophage involvement and chromosomal aberrations of bone marrow plasma cells.Leukemia 1997; 11: 1318–23.

    Article  PubMed  CAS  Google Scholar 

  15. Lesprit P, Godeau B, Authier FJ, et al. Pulmonary hypertension in POEMS syndrome: a new feature mediated by cytokines.Am J Respir Crit Care Med 1998; 157: 907–11.

    PubMed  CAS  Google Scholar 

  16. Lesprit P, Authier FJ, Gherardi R, et al. Acute arterial obliteration: a new feature of the POEMS syndrome?Medicine 1996; 75: 226–32.

    Article  PubMed  CAS  Google Scholar 

  17. Feinberg L, Temple D, de Marchena E, Patarca R, Mitrani A. Soluble immune mediators in POEMS syndrome with pulmonary hypertension: case report and review of the literature.Crit Rev Oncog 1999; 10: 293–302.

    PubMed  CAS  Google Scholar 

  18. Soubrier MJ, Dubost JJ, Sauvezie BJ. POEMS syndrome: a study of 25 cases and a review of the literature. French Study Group on POEMS syndrome.Am J Med 1994; 97: 543–53.

    Article  PubMed  CAS  Google Scholar 

  19. Paciocco G, Bossone E, Erba H, Rubenfire M. Reversible pulmonary hypertension in POEMS syndrome: another etiology of triggered pulmonary vasculopathy?Can J Cardiol 2000; 16: 1007–101.

    PubMed  CAS  Google Scholar 

  20. Blade J, Samson D, Reece D, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated with high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Bone and Marrow Transplant.Br J Haematol 1998; 102: 1115–23.

    Article  PubMed  CAS  Google Scholar 

  21. Bardwick PA, Zvaifler NJ, Gill GN, Newman D, Greenway GD, Resnick DL. Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome. Report on two cases and a review of the literature.Medicine 1980; 59: 311–22.

    Article  PubMed  CAS  Google Scholar 

  22. Yaqub S, Moder KG, Lacy MQ. Severe, reverversible pulmonary hypertension in a patient with monoclonal gammopathy and features of dermatomyositis.Mayo Clin Proc 2004; 79: 687–9.

    Article  PubMed  Google Scholar 

  23. Antonioli E, Nozzoli C, Gianfaldoni G, et al. Pulmonary hypertension related to thalidomide therapy in refractory multiple myeloma.Ann Oncol 2005; 16: 1849–50.

    Article  PubMed  CAS  Google Scholar 

  24. Sinisalo M, Hietaharju A, Sauranen J, Wirta O. Thalidomide in POEMS syndrome: case report.Am J Hematol 2004; 76: 66–8.

    Article  PubMed  Google Scholar 

  25. Watanabe O, Maruyama I, Arimura K, et al. Overproduction of vascular endothelial growth factor/vascular permeability factor is causative in Crow-Fukase (POEMS) syndrome.Muscle Nerve 1998; 21: 1390–7.

    Article  PubMed  CAS  Google Scholar 

  26. Soubrier M, Dubost JJ, Serre AF, et al. Growth factors in POEMS syndrome: evidence for a marked increase in circulating vascular endothelial growth factor.Arthritis Rheum 1997; 40: 786–7.

    Article  PubMed  CAS  Google Scholar 

  27. Shiue ST, McNally DP. Pulmonary hypertension from prominent vascular involvement in diffuse amyloidosis.Arch Intern Med 1988; 148: 687–9.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Cardiologia Generale 1, Dipartimento di Area Critica Medico Chirurgica, Università degli Studi, Viale Morgagni 85, 50134, Firenze, Italy

    Carlo Rostagno

  2. SOD Haematology, University of Florence, Florence, Italy

    Stefania Ciolli

  3. Thrombosis Centre, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy

    Domenico Prisco

Authors
  1. Carlo Rostagno
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  2. Stefania Ciolli
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  3. Domenico Prisco
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Corresponding author

Correspondence to Carlo Rostagno.

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Rostagno, C., Ciolli, S. & Prisco, D. An unusual case of pulmonary hypertension in a young male. Int Emergency Med 1, 127–132 (2006). https://doi.org/10.1007/BF02936537

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