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Dispersion and holdup in a three-phase fluidized-bed bioreactor

  • Brian H. Davison
Session 3 Bioengineering research

Abstract

Axial dispersion and phase holdup measurements were made using electroconductivity in a fermenting fluidized-bed bioreactor (FBR) and in a model nonfermenting three-phase FBR. Multiple axial conductivity probes were used to nonintrusively monitor the bed conductivity. The gas phase holdup was estimated from a ratio of the average bed conductivity and bulk conductivity. The solid fraction in the three-phase FBR can be estimated from the two-phase liquid-solid FBR. The response to a salt pulse was used to estimate the liquid axial dispersion coefficient. Particle Peclet numbers on the order of 10-2 were estimated as a function of flowrates and compared to literature correlations.

Index Entries

Three-phase fluidized-bed bioreactor columnar hydrodynamics fermentation 

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Copyright information

© Humana Press Inc. 1989

Authors and Affiliations

  • Brian H. Davison
    • 1
  1. 1.Chemical Technology DivisionOak Ridge National LaboratoryOak Ridge

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