Clinical and experimental studies on Composite Divitriol Infusion in treating tinea manum

  • Yang Zhibo
  • Ouyang Heng
  • Li Xianchun
Original Articles


Objective: To investigate the effect of Composite Divitriol Infusion (CDI) in treating tinea manum and study its antimycotic action.Methods: CDI was used to treat 139 patients with tinea manum and compared with Tinea Unguium Infusion in treating 77 cases as control. The experimental study in vivo was done, and electron microscopy (EM) was used to observe the therapeutical effect of CDI.Results: Among the 139 patients of the CDI group, 104 were cured, 21 markedly effective, 10 improved and 4 ineffective, the cure and markedly effective rate being 89.9%. The difference of effect between the CDI group and the control group was significant statistically (X2>12.84,P < 0.005). The antimycotic action of CDI was studied in vitro. The minimum inhibitory concentration (MIC) of CDI were about 0.25% for Trichophyton rubrum and 0.5% for Trichophyton gypseum and Microsporum gypseum. Trichophyton rubrum immersed with CDI showed that the mycelia became roughened, deformed, and macroconidium became smaller under EM.Conclusion: CDI is valuable in treating tinea manum.

Key Words

Composite Divitriol Infusion tinea manum Chinese herbal medicine therapy 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. l.
    1995; 24(2): 101–102.Google Scholar
  2. 2.
    1995; 9(3): 145–146.Google Scholar
  3. 3.
    MBC 1986; 19(6): 344–345.Google Scholar
  4. 4.
    1980; 7(5): 386.Google Scholar
  5. 5.
    1984; 13(3): 9–14.Google Scholar
  6. 6.
    1985; (5):19–22.Google Scholar

Copyright information

© The Chinese Journal of Integrated Traditional and Western Medicine Press 1999

Authors and Affiliations

  • Yang Zhibo
    • 1
  • Ouyang Heng
    • 1
  • Li Xianchun
    • 2
  1. 1.The Second Affiliated HospitalHunan College of TCMChangsha
  2. 2.Xiyang HospitalLoudi

Personalised recommendations