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Effect of xiaoke granule on blood sugar and blood rheological property in experimental diabetic animals

  • Xiao-mei Ji
  • Gen-Shang Liu
  • Fang Qi
  • Hu-Zhan Zheng
  • Jing She
  • Mu-Xin Gong
  • Jun Sun
  • Hong-ying Zhang
Article
  • 16 Downloads

Abstract

Objective

To study the pharmacological effect of Xiaoke Granule on blood sugar and blood rheological property in the diabetic animals.

Methods

Alloxan induced diabetic mice or rats were grouped randomly. The effects of XKG on blood sugar, appetite, capacity of drinking, glucose tolerance, blood lipid and blood rheological property were observed and compared among groups.

Results

XKG showed a trend in reducing the appetite and capacity of drinking, increasing the body weight, and significantly inhibiting the increase of blood sugar coused by ectogenic glucose in mice, and could improve the blood lipid and blood rheological property in rats.

Conclusion

XKG is effective in reducing serum total cholesterol, lowering the blood viscosity, improving the blood rheological property of alloxan induced diabetic animals. Therefore, it might effective in treating and preventing the occurrence of diabetes mellitus and the complications of blood stasis.

Key words

Xiaoke Granule blood sugar blood rheological property glucose tolerance diabetes mellitus 

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References

  1. 1.
    QI F, LIU GS, JI XM, QI F, et al. Clinical research on effect of Xiaoke Granule in treating type II diabetes mellitus. Beijing J Traditional Chinese Medicine 1998; (4): 42.Google Scholar
  2. 2.
    Chen GT, Xue SQ. Newest Standards of Diagnosis and Treatment at Home and Abroad. Beijing: Xueyuan Publishing House, 1991: 510.Google Scholar

Copyright information

© The Chinese Journal of Integrated Traditional and Western Medicine Press 2002

Authors and Affiliations

  • Xiao-mei Ji
    • 1
  • Gen-Shang Liu
    • 1
  • Fang Qi
    • 1
  • Hu-Zhan Zheng
    • 2
  • Jing She
    • 3
  • Mu-Xin Gong
    • 1
  • Jun Sun
    • 1
  • Hong-ying Zhang
    • 1
  1. 1.School of Traditional Chinese Medicine and PharmacyCapital University of Medical SciencesBeijing
  2. 2.Beijing University of TCMChina
  3. 3.State Administration of Traditional Chinese MedicineChina

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