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Effect of xiaoke granule on blood sugar and blood rheological property in experimental diabetic animals

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Abstract

Objective

To study the pharmacological effect of Xiaoke Granule on blood sugar and blood rheological property in the diabetic animals.

Methods

Alloxan induced diabetic mice or rats were grouped randomly. The effects of XKG on blood sugar, appetite, capacity of drinking, glucose tolerance, blood lipid and blood rheological property were observed and compared among groups.

Results

XKG showed a trend in reducing the appetite and capacity of drinking, increasing the body weight, and significantly inhibiting the increase of blood sugar coused by ectogenic glucose in mice, and could improve the blood lipid and blood rheological property in rats.

Conclusion

XKG is effective in reducing serum total cholesterol, lowering the blood viscosity, improving the blood rheological property of alloxan induced diabetic animals. Therefore, it might effective in treating and preventing the occurrence of diabetes mellitus and the complications of blood stasis.

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References

  1. QI F, LIU GS, JI XM, QI F, et al. Clinical research on effect of Xiaoke Granule in treating type II diabetes mellitus. Beijing J Traditional Chinese Medicine 1998; (4): 42.

  2. Chen GT, Xue SQ. Newest Standards of Diagnosis and Treatment at Home and Abroad. Beijing: Xueyuan Publishing House, 1991: 510.

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Authors and Affiliations

  1. School of Traditional Chinese Medicine and Pharmacy, Capital University of Medical Sciences, 100007, Beijing

    Xiao-mei Ji, Gen-Shang Liu, Fang Qi, Mu-Xin Gong, Jun Sun & Hong-ying Zhang

  2. Beijing University of TCM, China

    Hu-Zhan Zheng

  3. State Administration of Traditional Chinese Medicine, China

    Jing She

Authors
  1. Xiao-mei Ji
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  2. Gen-Shang Liu
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  3. Fang Qi
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  4. Hu-Zhan Zheng
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  5. Jing She
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  6. Mu-Xin Gong
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  7. Jun Sun
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  8. Hong-ying Zhang
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Corresponding author

Correspondence to Xiao-mei Ji.

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Ji, Xm., Liu, GS., Qi, F. et al. Effect of xiaoke granule on blood sugar and blood rheological property in experimental diabetic animals. CJIM 8, 212–214 (2002). https://doi.org/10.1007/BF02934314

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  • DOI: https://doi.org/10.1007/BF02934314

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