Semicontinuous production of red pigment by immobilized cells ofBacillus sp. BH-99 using column bioreactor
The semicontinuous production of red pigment by immobilized cells ofBacillus sp. BH-99 was investigated in comparison with free cells. The red pigment produced highest productivity under the conditions of aeration of 0.2 mL/min and 2 mm diameter of gel beads by using 3.0% sodium alginate. Semicontinuous production by immobilized cells showed the highest productivity with replacement of fresh production medium in every 72 h for fourth fermentation cycle following the conditions of red pigment productivity.
Keywordsred pigment immobilized cell colloidal chitin Bacillus sp.
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