Antioxidant properties ofErigeron annuus extract and its three phenolic constituents



The antioxidant activity of the extract ofErigeron annuus was assessed by means of two differentin vitro tests: bleaching of the stable 1,1-diphenyl-2-picrylhydrazyl radical (DPPH test) and the scavenging of authentic peroxynitrite in company with peroxynitrite generation from 3-morpholinosydnonimine (SIN-1). In both tests, the 85% aq. MeOH andn-BuOH soluble fractions of the crude extract showed a significant scavenging effect on peroxynitrite and DPPH radical in comparison to L-ascorbic acid. And bioassay-guided fractionation of then-BuOH soluble fraction led to the isolation of three compounds: Apigenin (1), quercetin-3-O-glucoside (2), and caffeic acid (3). The structures of the isolated compounds were elucidated on the basis of their spectroscopic data and their antioxidant activities were measured by determining their capacity to scavenge peroxynitrite and the DPPH radical.


Erigeron annuus authentic peroxynitrite (ONOO3-morpholinosydnonimine (SIN-1) 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) 


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Copyright information

© The Korean Society for Biotechnology and Bioengineering 2006

Authors and Affiliations

  1. 1.Research Institute of Marine Science and Technology (RIMST)Korea Maritime UniversityBusanKorea
  2. 2.Division of Marine Environment and BioscienceKorea Maritime UniversityBusanKorea

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