The levels of anti-Candida antibodies were determined in experimental animals immunized with 4 different yeast doses (0.3, 0.6, 1.2, 2.4 × 108 CFU) at weekly intervals. After immunization (sampling intervals 1, 2, and 3 months), the intravenous blood was examined for the presence of serum anti-Candida antibodies. After one month, the titers of anti-Candida antibodies reached 1:40–1:1280 and remained at the same level after two months in the majority of animals; only in a few of them the titers increased or were detectedde novo. After three months, when the animals were no longer immunized, a decreasing trend in antibody titers was detected in the majority of animals.
Antibody Titer Oral Cavity Neonatal Intensive Care Unit Invasive Fungal Infection Invasive Candidiasis
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