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Folia Microbiologica

, Volume 48, Issue 4, pp 555–558 | Cite as

The detection of anti-Candida antibodies on experimental animal models

  • E. Pilipčinec
  • E. Dorko
  • L’. Tkáčiková
  • A. Wantrubová
  • A. Bugarský
Article

Abstract

The levels of anti-Candida antibodies were determined in experimental animals immunized with 4 different yeast doses (0.3, 0.6, 1.2, 2.4 × 108 CFU) at weekly intervals. After immunization (sampling intervals 1, 2, and 3 months), the intravenous blood was examined for the presence of serum anti-Candida antibodies. After one month, the titers of anti-Candida antibodies reached 1:40–1:1280 and remained at the same level after two months in the majority of animals; only in a few of them the titers increased or were detectedde novo. After three months, when the animals were no longer immunized, a decreasing trend in antibody titers was detected in the majority of animals.

Keywords

Antibody Titer Oral Cavity Neonatal Intensive Care Unit Invasive Fungal Infection Invasive Candidiasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 2003

Authors and Affiliations

  • E. Pilipčinec
    • 1
  • E. Dorko
    • 3
  • L’. Tkáčiková
    • 1
  • A. Wantrubová
    • 1
  • A. Bugarský
    • 2
  1. 1.Department of Microbiology and ImmunologyUniversity of Veterinary MedicineKošiceSlovakia
  2. 2.Department of Forensic and Public Veterinary MedicineUniversity of Veterinary MedicineKošiceSlovakia
  3. 3.Department of Physiology, Faculty of MedicineŠafárik UniversityKošiceSlovakia

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