Folia Microbiologica

, Volume 30, Issue 4, pp 393–395 | Cite as

Secondary metabolism and pathophysiology

  • Z. Vaněk
  • M. Blxtmauerová


Mechanisms of regulation of biosynthesis of secondary metabolites in microorganisms under natural conditions differ from the regulation mechanisms resulting in an overproduction of these metabolites in industrial fermentations. The overproduction is attained by creating pathophysiological cultivation conditions and by using mutant strains which differ substantially from wild strains isolated from natural environment.


Secondary Metabolite Secondary Metabolism Wild Strain Cell Reproduction Rifamycin 
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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1985

Authors and Affiliations

  • Z. Vaněk
    • 1
  • M. Blxtmauerová
    • 1
  1. 1.Institute of MicrobiologyCzechoslovak Academy of SciencesPrague 4

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