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Correction method for estimating the number of reversions in bacteria

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Abstract

A correction of the results of mutation tests in bacteria during the induction of reversions from auxotrophy to prototrophy is described. The correction is based on a calibration curve of the spontaneous frequency of reversions and is suitable for testing doses of mutagens that exhibit a pronounced lethal effect.

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References

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Author notes

  1. E. Říhová

    Present address: Institute of Experimental Botany, Czechoslovak Academy of Sciences, 370 05, České Budějovice, Czechoslovakia

Authors and Affiliations

  1. Department of Genetics, Faculty of Sciences, Charles University, Prague 2

    E. Říhová

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  1. E. Říhová
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Říhová, E. Correction method for estimating the number of reversions in bacteria. Folia Microbiol 26, 426–429 (1981). https://doi.org/10.1007/BF02927340

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  • DOI: https://doi.org/10.1007/BF02927340

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