Correction method for estimating the number of reversions in bacteria
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A correction of the results of mutation tests in bacteria during the induction of reversions from auxotrophy to prototrophy is described. The correction is based on a calibration curve of the spontaneous frequency of reversions and is suitable for testing doses of mutagens that exhibit a pronounced lethal effect.
KeywordsAITC Ethyl Methanesulfonate Allylisothiocyanate Selective Plate Revertant Coloni
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- Green M.H.L., Muriel W.J.: Mutagen testing usingtrp + reversion inEscherichia coli.Mutation Bes. 38, 3 (1976).Google Scholar
- de Mitchell G.I.: Microbial assays for mutagenicity: A modified liquid culture method compared with the agar plate system for precision and sensitivity.Mutation Bes. 54, 1 (1978).Google Scholar