Folia Microbiologica

, Volume 24, Issue 4, pp 352–363 | Cite as

Physiological characterictics and energy balance ofKlebsiella aerogenes in a multistage tower fermentor

  • J. Páca


Biomass growth, consumption of carbon and energy source, specific rates of formation of metabolic byproducts, biomass yield referred to the C-source and to oxygen, respiration rate and the value ofRQ were studied inKlebsiella aerogenes CCM 2318 (on a synthetic glucose medium) at different specific growth rates. Maintenance coefficients and the total energy balance of the cultivation process were evaluated for a multistage tower fermentor with a defined interstage mixing. The results pointed to changes in both glucose metabolism and the physiological state of the population, brought about by changes in specific growth rate. As compared with a chemostat, the culture was found to exhibit a different physiological character in stages 1 and 4 despite a considerable interstage mixing.


Specific Growth Rate Dilution Rate Oxygen Limitation Oxygen Transfer Rate Chemostat Culture 


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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1979

Authors and Affiliations

  • J. Páca
    • 1
  1. 1.Department of Fermentation Chemistry and TechnologyInstitute of Chemical TechnologyPrague 6

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