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Properties and participation of “free” endotoxin in the toxic activity ofMorganella morganii

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Abstract

“Free” and “bound”Morganella morganii endotoxin was characterized by chemical (determination of proteins, saccharides and 3-deoxy-2-octulosonic acid) and immunochemical (double-diffusion test, immunoelectrophoresis, tandem crossed immunoelectrophoresis) methods. Chemical analysis showed that ”free“ endotoxin contains more protein and phosphorus and legs sacoharides than bound endotoxin. Immunochemical tests revealed differences in the structure of polysaccharide portions of both endotoxins, and, on the other hand, identity of certain antigenic determinants. Free endotoxin possessed a higher biological activity.

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Bartková, G., Majtán, V. Properties and participation of “free” endotoxin in the toxic activity ofMorganella morganii . Folia Microbiol 33, 323–328 (1988). https://doi.org/10.1007/BF02925628

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