Skip to main content
Log in

Economic evaluation of a multicompartment bioreactor for ethanol production usingIn Situ extraction of ethanol

  • Published:
Applied Biochemistry and Biotechnology Aims and scope Submit manuscript

Abstract

We have previously described a multicompartment reactor that can be used with yeast (Saccharomyces cerevisiae) for ethanol production from a starch hydrolysate. By separating a solvent layer (tri-normal-butylphosphate, or TBP) from a cell layer, ethanol was extractedin situ and phase toxicity was prevented. Pressure cycling of the gas phase can be used to reduce significantly mass-transfer limitations that often limit entrapped-cell systems. A preliminary economic evaluation shows that with TBP the multicompartment reactor is generally more economically favorable at low volumes, and the traditional system is more favorable at high volumes. Improved solvents can increase economic viability at high volumes (108 L/yr of 95% ethanol).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Vick Roy, T. B., Blanch, H. W., and Wilke, C. R. (1983),Trends Biotechnol. 1, 135–139.

    Article  Google Scholar 

  2. Ghose, T. K. and Tyagi, R. D. (1979),Biotechnol. Bioeng. 21, 1401–1420.

    Article  CAS  Google Scholar 

  3. Holzberg, I., Finn, R. K., and Steinkraus, K. H. (1967),Biotechnol. Bioeng. 9, 413–427.

    Article  CAS  Google Scholar 

  4. Wada, M., Kato, J., and Chibata, I. (1980),Eur. J. Appl. Microbiol. 10, 275–287.

    Article  CAS  Google Scholar 

  5. Brink, L. E. S. and Tramper, J. (1985),Biotechnol. Bioeng. 27, 1258–1269.

    Article  CAS  Google Scholar 

  6. Cysewski, G. R. and Wilke, C. R. (1977),Biotechnol. Bioeng. 19, 1125–1143.

    Article  CAS  Google Scholar 

  7. Roffler, S. R., Blanch, H. W., and Wilke, C. R. (1984),TrendsBiotechnol. 2, 129–136.

    CAS  Google Scholar 

  8. Bui, S., Veryklos, X., and Mutharasan, R. (1985),Ind. Eng. Chem. Process Des. Dev. 24, 1209–1213.

    Article  CAS  Google Scholar 

  9. Tangu, S. K. and Ghose, T. R. (1970),Process Biochem. Aug./Sept., 24–27.

  10. Friedman, M. R. and Gaden, E. L., Jr. (1970),Biotechnol. Bioeng. 12, 577–589.

    Article  Google Scholar 

  11. Minier, M. and Goma, G. (1982),Biotechnol. Bioeng. 24, 1565–1579.

    Article  CAS  Google Scholar 

  12. Matsumara, M. and Markl, H. (1986),Biotechnol. Bioeng. 28, 534–541.

    Article  Google Scholar 

  13. Mehta, G. D. and Fraser, M. D. (1985),Ind. Eng. Chem. Process Des. Dev. 24, 556–560.

    Article  CAS  Google Scholar 

  14. Kollerup, F. and Dauguilis, A. J. (1987),Ann. N.Y. Acad. Sci. 506, 478–491.

    Article  CAS  Google Scholar 

  15. Maiorella, B. L., Blanch, H. W., and Wilke, C. R. (1984),Biotechnol. Bioeng. 26, 1003–1025.

    Article  CAS  Google Scholar 

  16. Roddy, J. W. (1981),Ind. Eng. Chem. Process Des. Dev. 20, 104–108.

    Article  CAS  Google Scholar 

  17. Ishii, S., Taya, M., and Kobayashi, T. (1985),J. Chem. Eng. (Japan)18, 125–130.

    CAS  Google Scholar 

  18. Murphy, T. K., Blanch, H. W., and Wilke, C. R. (1982),Process Biochem. 17(6), 6–9.

    CAS  Google Scholar 

  19. Cho, T. and Shuler, M. L. (1986),Biotechnol. Prog. 2, 53–60.

    Article  CAS  Google Scholar 

  20. Frank, G. T. and Sirkar, K. K. (1986),Biotechnol. Bioeng. Symp. 17, 303–316.

    CAS  Google Scholar 

  21. Frank, G. T. and Sirkar, K. K. (1985),Biotechnol. Bioeng. Symp. 15, 621–631.

    Google Scholar 

  22. Efthymiou, G. S. and Shuler, M. L. (1987),Biotechnol. Prog. 3, 259–264.

    CAS  Google Scholar 

  23. Steinmeyer, D. E. and Shuler, M. L. (1990),Biotechnol. Prog. 6, 286–291.

    Article  CAS  Google Scholar 

  24. Steinmeyer, D. E. and Shuler, M. L. (1989),Chem. Eng. Sci.. 44, 2017–2030.

    Article  CAS  Google Scholar 

  25. Steinmeyer, D. E. and Shuler, M. L. (1990),Biotechnol. Prog. 6, 362–369.

    Article  CAS  Google Scholar 

  26. Watson, E. K., Rickelton, W. A., Robertson, A. J., and Brown, T. J., Cyanamid Canada (unpublished).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shuler, M.L., Steinmeyer, D.E., Togna, A.P. et al. Economic evaluation of a multicompartment bioreactor for ethanol production usingIn Situ extraction of ethanol. Appl Biochem Biotechnol 28, 571–588 (1991). https://doi.org/10.1007/BF02922634

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02922634

Index Entries

Navigation