Abstract
We have previously described a multicompartment reactor that can be used with yeast (Saccharomyces cerevisiae) for ethanol production from a starch hydrolysate. By separating a solvent layer (tri-normal-butylphosphate, or TBP) from a cell layer, ethanol was extractedin situ and phase toxicity was prevented. Pressure cycling of the gas phase can be used to reduce significantly mass-transfer limitations that often limit entrapped-cell systems. A preliminary economic evaluation shows that with TBP the multicompartment reactor is generally more economically favorable at low volumes, and the traditional system is more favorable at high volumes. Improved solvents can increase economic viability at high volumes (108 L/yr of 95% ethanol).
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Shuler, M.L., Steinmeyer, D.E., Togna, A.P. et al. Economic evaluation of a multicompartment bioreactor for ethanol production usingIn Situ extraction of ethanol. Appl Biochem Biotechnol 28, 571–588 (1991). https://doi.org/10.1007/BF02922634
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DOI: https://doi.org/10.1007/BF02922634