Abstract
The method of highly selective potentiometric detection of bioactive substances developed by us has been much improved by using tantalum metal as a electrode material, by employment of a new method of modification (using γ-aminopropyltriethoxysilane and cyanogen bromide), and by the pretreatment with inert protein before the measurement. As the consequence, the response in the electrode potential shift has been increased and the reproducibility of the data reached almost 100%.
Similar content being viewed by others
References
Yamamoto, N., Nagasawa, Y., Sawai, M., Sudo, T., and Tsubomura, H. (1978),J. Immunol. Method. 22, 309.
Yamamoto, N., Shuto, S., and Tsubomura, H. (1980),J. Chem. Soc. Jpn. 10, 1562.
Yamamoto, N., Nagasawa, Y., Shuto, S., Tsubomura, H., Sawai, M., and Okumura, H. (1980),Clin. Chem. 26, 1569.
Yamamoto, N., Shuto, S., Tsubomura, H., Sawai, M., and Okumura, H. (1981),Appl. Biochem. Biotech. 6, 319.
Yamamoto, N., Tsubomura, H., and Sawai, M. (1981),Proc. Jpn. Acad. 57, 123.
Yamamoto, N., Nagaoka, S., Tanaka, T., Shiro, T., Honma, K., and Tsubomura, H. (1983),Proc. International Meeting on Chemical Sensors, 699 Kodansha-Elsevier.
Someno, Yasumori, ed., (1976), “Hyomenbunseki (Surface Analysis)”, Kodansha.
Pütter, J. (1967),Z. Physiol. Chem. 348, 1197.
Lerner, H., Zahradnik, R. T., and Buchbinder, M. (1982),IEEE Trans. Biomed. Eng. 29, 290.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tsuruta, H., Tsubomura, H. Potentiometric studies of selective reactions of bioactive substances on the surface-modified tantalum electrodes. Appl Biochem Biotechnol 19, 151–162 (1988). https://doi.org/10.1007/BF02921480
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02921480