Strain screening and development for industrial lactic acid fermentation
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Thirty-four lactic acid bacterial strains have been screened for their potential in industrial lactic acid fermentations. The screening criteria included substrate utilization, product yield, resistance to product inhibition, product stereospecificity, growth temperature, fermentation rate, and ease of cell-broth separation. Acclimation techniques were also used to increase growth temperature and improve product tolerance. This effort has resulted in the identification and improvement of several promising strians, and a superior mixed culture. The mixed culture exhibited a >98% product stereospecificity, cell viability at 106.6 g/L lactic acid, and a productivity of 5.3 g/(L·h) in batch fermentation.
Index EntriesLactic acid fermentation strain development stereospecific product inhibition
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- 1.Seely, R. S. (1992),Chem. Bus. 14, 28–30.Google Scholar
- 2.Vick Roy, T. B. (1985), inComprehensive Biotechnology, vol. 3, The Practice of Biotechnology: Commodity Products, Blanch, H. W., Drew, S., and Wang, D. I. C., eds., Pergamon Press, Elmsford, NY, pp. 761–776.Google Scholar
- 6.Sandine, W. E. (1989), inDevelopments in Industrial Microbiology, vol. 30, Cooney, J. and Sebek, O., eds., Elsevier, Amsterdam, The Netherlands, pp. 1–9.Google Scholar
- 7.Lipinsky, E. S. and Sinclair, R. G. (1986),Chem. Eng. Prog. 82, 26–32.Google Scholar
- 9.McDonald, L. C., Fleming, H. P., and Hassan, H. M. (1990),Appl. Environ. Microbiol. 56, 2120–2124.Google Scholar
- 10.Viniegra-Gonzalez, G. and Gomez, J. (1984), inBioconversion Systems, Wise, D. L., ed., CPC Press, Boca Raton, FL, pp. 17–39.Google Scholar