Applied Biochemistry and Biotechnology

, Volume 41, Issue 1–2, pp 59–66 | Cite as

Highly sensitive immunosensor with a surface photovoltage technique

  • Teruaki Katsube


An ac surface photo voltage technique was successfully applied to construct a highly sensitive immuno-sensor by reducing the ion screening effect. A low noise amplification was attained by using a phase sensitive amplification technique, which made it possible to use low-ion density electrolyte leading to suppress the ion screening effect. The response voltage attained was as high as 7 mV for the detection of 10−8 M IgG antigen with a signal-to-noise ratio of 104.


Apply Biochemistry Surface Charge Density Response Voltage Surface Photovoltage Surface Voltage 
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Copyright information

© Humana Press Inc 1993

Authors and Affiliations

  • Teruaki Katsube
    • 1
  1. 1.Faculty of EngineeringSaitama UniversityUrawa, SaitamaJapan

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