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Dietary zinc deficiency has no effect on auditory brainstem responses in the rat

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Abstract

Zinc has been shown to effect—in vitro—a number of processes associated with neurotransmission. We have tested whether the rate of impulse conduction—in vivo—as measured from the latencies of auditory brainstem responses (ABR), is influenced by dietary zinc deficiency in the rat.

Dietary zinc deficiency for up to 26 wk had no effect on the wave I–IV interval compared to zinc-adequate fed animals. The results are discussed in relation to the observed constancy of brain overall and extracellular fluid zinc concentrations under conditions of dietary zinc deficiency.

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Authors and Affiliations

  1. Department of Radiochemistry, Interfaculty Reactor Institute, Technical University, Mekelweg 15, 2629 JB, Delft, The Netherlands

    Jan Wensink & Cornelis J. A. Van Den Hamer

  2. Department of Ear, Nose and Throat, Faculty of Medicine, Erasmus University, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands

    Hans Hoeve & Ingrid Mertens Zur Borg

Authors
  1. Jan Wensink
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  2. Hans Hoeve
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  3. Ingrid Mertens Zur Borg
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  4. Cornelis J. A. Van Den Hamer
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Wensink, J., Hoeve, H., Borg, I.M.Z. et al. Dietary zinc deficiency has no effect on auditory brainstem responses in the rat. Biol Trace Elem Res 22, 55–62 (1989). https://doi.org/10.1007/BF02917416

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  • DOI: https://doi.org/10.1007/BF02917416

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