Endocrine Pathology

, 1:245 | Cite as

Multiple myeloma presenting as a sellar plasmacytoma and mimicking a pituitary tumor: Report of a case and a review of the literature

  • AI-Noor N. Dhanani
  • Juan M. Bilbao
  • Kalman Kovacs
Case Report


A case of multiple myeloma presenting as a plasmacytoma and mimicking a pituitary tumor is reported. The importance of recognizing the existence of plasmacytoma in the differential diagnosis of sellar and parasellar tumors is stressed, as it leads to important differences in management. The literature is reviewed. Patients presenting with plasmacytoma with symptoms of a pituitary adenoma have an average age of 58 years; the male to female ratio is 3:1; diplopia, headache, and progressive visual loss are the most important symptoms; third, sixth, and fourth cranial nerve palsies are the most common signs; and pituitary function is usually normal. CT scan of the sellar region is the imaging modality of choice; pathologically, light and electron microscopy are invaluable in making the correct diagnosis. Making the correct diagnosis allows further appropriate investigation for systemic disease and consequent management.


Multiple Myeloma Pituitary Adenoma Pituitary Tumor Cranial Nerve Palsy Pituitary Function 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Humana Press Inc. 1990

Authors and Affiliations

  • AI-Noor N. Dhanani
    • 1
  • Juan M. Bilbao
    • 1
  • Kalman Kovacs
    • 1
  1. 1.Department of Pathology, St. Michael’s HospitalUniversit of TorontoTorontoCanada

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