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KLF6mRNA expression in primary hepatocellular carcinoma

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Summary

To investigate the expression of KLF6mRNA in primary hepatocellular carcinoma (HCC), nomal liver tissues and the tissues adjacent to the cancers, reverse-transcription polymerase chain reaction (RT-PCR) was employed to investigate the expression of the KLF6 gene in HCC, the corresponding adjacent non-cancerous tissues and normal liver tissue. Our results showed that an amplified fragment of 127 bp DNA was detected in 18 of 19 (94.7%) adjacent non-cancerous tissues and normal liver tissue, and in 12 (85.7%) of 11 HCC. There were no significant differences in the levels of KLF6 mRNA between normal liver and liver tumors (P>0.05). It is concluded that KLF6 mRNA is generally expressed in HCC.

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Authors and Affiliations

  1. Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China

    Wang Shaoping, Chen Xiaoping, Zhang Wanguang & Qiu Fazu

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  1. Wang Shaoping
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  2. Chen Xiaoping
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  3. Zhang Wanguang
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  4. Qiu Fazu
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Additional information

Wang Shaoping made born in 1965. Associate Professor

This study was supported by the Clinical Key Discipline of Chinese Ministry of Public Health (No. 200 321).

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Shaoping, W., Xiaoping, C., Wanguang, Z. et al. KLF6mRNA expression in primary hepatocellular carcinoma. Current Medical Science 24, 585–587 (2004). https://doi.org/10.1007/BF02911362

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  • DOI: https://doi.org/10.1007/BF02911362

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