Use of bacteriostats in soap and household cleansing agents

  • Leonard J. Vinson


In recent years there has been increasing use of antibacterial agents employed in toilet bars to provide deodorant and degerming activity. The common desirable properties of these agents are antibacterial activity at low concentrations, skin substantivity, acceptable color and odor, compatibility with the vehicle, and low irritation and sensitization potential.

Bacteriostats used for such pruposes are principally bisphenolies, halogenated salicylanilides, and halogenated carbanilides. Methods for assessing their effectiveness and safety are discussed. The polybrominated salicylanilides represent a versatile group of bacteriostats which enjoys increasing acceptability in toilet bars and also provides benefits in such household products as liquid detergents, granulated detergents, hard-surface disinfectant cleansers, and aerosol disinfectant sprays.


Liquid Detergent Skin Secretion Hexachlorophene Cosmetic Chemist Photosensitize Potential 
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  1. 1.
    Ortenzio, L. F., and L. S. Stuart, J. Offic. Agr. Chem.,44, 416–421 (1961).Google Scholar
  2. 2.
    Vinson, L. J., and O. M. Dickinson, Soap and Chem. Specialties40, 76 (1964).Google Scholar
  3. 3.
    Vinson, L. J., P. Dineen, and W. C. Schneider, Ibid.37, 45–48, 117–121; Nov. 61–64, 110–111 (1961).Google Scholar
  4. 4.
    Vinson, L. J., E. L. Ambye, A. G. Bennett, W. C. Schneider and J. J. Travers, J. Pharm. Sci.50, 827–830 (1961).CrossRefGoogle Scholar
  5. 5.
    Travers, J. J., A. C. Rohloff, E. L. Ambye and L. J. Vinson, J. Soc. Cosmetics Chemists10, 410–421 (1959).Google Scholar
  6. 6.
    Jillson, O. F., and R. D. Baughman, Arch. Derm.88, 409–418 (1963).Google Scholar
  7. 7.
    Epstein, S., and T. Enta, JAMA194, 1016–1017 (1965).CrossRefGoogle Scholar
  8. 8.
    Molloy, J. F., and J. A. Mayer, Arch. Derm.93, 329–331 (1966).CrossRefGoogle Scholar
  9. 9.
    Harber, L. C., et al., Arch. Derm.94, 255–262 (1966).CrossRefGoogle Scholar
  10. 10.
    Wilkinson, D. S., Brit. J. Derm.73, 213 (1961).CrossRefGoogle Scholar
  11. 11.
    Vinson, L. J., and R. S. Fiatt, J. Invest. Derm.38, 327–328 (1962).Google Scholar
  12. 12.
    Vinson, L. J., and V. F. Borselli, J. Soc. Cosmetic Chemists17, 123–130 (1966).Google Scholar
  13. 13.
    Peck, S. M., and L. J. Vinson, in press.Google Scholar

Copyright information

© The American Oil Chemists’ Society 1967

Authors and Affiliations

  • Leonard J. Vinson
    • 1
  1. 1.Lever Brothers Research CenterEdgewater

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