Ricerca in clinica e in laboratorio

, Volume 13, Issue 2, pp 255–260 | Cite as

Human papillomavirus in cervical condylomata

An immunohistochemical study
  • Gian Mario Mariuzzi
  • Carlo Alberto Beltrami
  • Carla Di Loreto
  • Michele De Nictolis
  • Daniela Stramazzotti
  • Mariella Portolani
  • Anna Maria Borgatti
  • Arcangelo Morresi
Original Contributions


Twenty-seven cervical condylomata were studied by morphological and immunohistochemical methods (peroxidase-antiperoxidase technique according to Sternberger, with some modifications). The antiserum was obtained from rabbits immunized by human papillomavirus virions; 37% of condylomata stained positively and the koilocytotic cells showed a dark brown nuclear stain. This technique, not particularly useful for diagnostic purposes, could be employed to obtain better understanding of the natural history of these cervical neoplasias.


Cervical condyloma Dysplasia-Ca in situ Human papillomavirus Immunoperoxidase Viral oncogenesis 


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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • Gian Mario Mariuzzi
    • 1
  • Carlo Alberto Beltrami
    • 1
  • Carla Di Loreto
    • 1
  • Michele De Nictolis
    • 1
  • Daniela Stramazzotti
    • 1
  • Mariella Portolani
    • 2
  • Anna Maria Borgatti
    • 3
  • Arcangelo Morresi
    • 4
  1. 1.Istituto di Anatomia ed Istologia PatologicaUniversità degli Studi di AnconaTorrette di Ancona (AN)Italia
  2. 2.Istituto di MicrobiologiaUniversità degli Studi di AnconaAnconaItalia
  3. 3.Istituto di Virologia e MicrobiologiaUniversità degli Studi di BolognaBolognaItalia
  4. 4.Reparto di Dermatologia e Chirurgia PlasticaINRCAAncona

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