Chinese Science Bulletin

, 46:1889 | Cite as

Localization of the brain calculation function area with MRI

  • Mingshi Wang
  • Liqun Wang


The aim of this study is to define the anatomical localization of corresponding brain function area during calculating. The activating modes in brain during continuous silent calculating subtraction and repeated silent reading multiplication table were compared and investigated. Fourteen volunteers of right-handedness were enrolled in this experiment. The quite difference of reaction modes in brain area during the two modes of calculation reveal that there are different processing pathways in brain during these two operating actions. During continuous silent calculating, the function area is localized on the posterior portion of superior and middle gyrus of frontal lobe and the lobule of posterior parietal lobe (P < 0.01,T = 5.41). It demonstrates that these function areas play an important role in the performance of calculation and working memory. Whereas the activating of visual cortex shows that even in mental arithmetic processing the brain action is having the aid of vision and visual space association.


functional magnetic resonance imaging fMRI ultilaminal EPI (echo planar imaging) human brain function localization temporary memory vision and visual space association 


  1. 1.
    Warrington, E. K., The fraction of arithmetical skills: A single case study, Q. J. Exp. Psychol. A, 1982, 34: 31.PubMedGoogle Scholar
  2. 2.
    Cohen, L., Dehaene, S., Amnesia for arithmetic factors: A single case study, Brain and Language, 1994, 47: 214.PubMedCrossRefGoogle Scholar
  3. 3.
    Hayashi, N., Kazunari, I., Hajime, K. et al., Regional differences in cerebral blood flow during recitation of the multiplication table and actual calculation: a position emission tomography study, J. Neurological Sci., 2000, 176: 102.CrossRefGoogle Scholar
  4. 4.
    Weaver, J. B., Monotonic noise suppression used to improve the sensitivity of fMRI activation maps, J. Digit Imaging, 1998, 11(3 Suppl 1): 46.PubMedCrossRefGoogle Scholar
  5. 5.
    Tkayama, Y., Sugishita, M., Akiguchi, I., Isolated acalculia due to left parietal lesion, Arch. Neurol., 1994, 51: 286.Google Scholar
  6. 6.
    Casey, B. J., Giedd, J. N., Thomas, K. M., Structural and functional brain development and its relation to cognitive development, Biol. Psychol., 2000, 54(1-3): 241.PubMedCrossRefGoogle Scholar
  7. 7.
    Ruxandra, S. C., Philippe, P., Pierre-Francois, V. D. M. et al., Understanding dissociations in dyscalculia: a brain imaging study of the impact of number size on the cerebral networks for exact and approximate calculation Brain, 2000, 123: 2240.CrossRefGoogle Scholar
  8. 8.
    Fockert, J. W., Rees, G., Frith, C. D. et al., The role of working memory in visual selective attention, Science, 2000, 291: 1803.CrossRefGoogle Scholar
  9. 9.
    Tulving, E., Craik, S., Moscovitch, F. J., Hemispheric encoding/retrieval asymmetry in episodic memory: Positron emission tomography findings, Proceedings of the National Academy of Science USA, 1991, 91: 2012.CrossRefGoogle Scholar
  10. 10.
    Menon, V., Rivera, S. M., White, C. D. et al., Functional optimization of arithmetic processing in perfect performers, Cog. Brain, 2000, 9: 343.CrossRefGoogle Scholar
  11. 11.
    Menon, V., Rivera, M., White, C. D. et al., Dissociating Prefrontal and Parietal Cortex activation during arithmetic processing, Neurolmage, 2000, 12: 357.CrossRefGoogle Scholar
  12. 12.
    Harmony, T., Fernandez, T., Silva, J. et al., Do specific EEG. frequencies indicate different processes during mental calculation? Neurosci. Lett., 1999, 266(1): 25.PubMedCrossRefGoogle Scholar
  13. 13.
    Campos-Castello, J., Neurological assessment of learning disorders, Rev. Neurol., 1998, 27(156): 280.PubMedGoogle Scholar

Copyright information

© Science in China Press 2001

Authors and Affiliations

  • Mingshi Wang
    • 1
  • Liqun Wang
    • 2
  1. 1.Tianjin UniversityTianjinChina
  2. 2.|Hightech Research Center, Super Conductive Electricity InstituteTokyo Denki UniversityJapan

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