Advertisement

Virchows Archiv B

, Volume 29, Issue 1, pp 225–228 | Cite as

Amyloid P component — A special type of collagen?

  • H. -M. Schneider
  • M. Loos
Short Communication
  • 10 Downloads

Summary

The localization of amyloid P-components is demonstrated by immunofluorescence microscopy in normal human tissue (kidney, spleen, liver). The relation to collagen and to amyloidosis is discussed.

Key words

Amyloid P-component Collagen 

References

  1. Kefalides, N.A.: A collagen of unusual composition and a glytoprotein isolated from canine glomerular basement membrane. Biochem. Biophys. Res. commun.22, 26–32 (1966)PubMedCrossRefGoogle Scholar
  2. Rojkind, M.: Reticulins. In: The biochemistry of disease, Vol. 3, Molecular pathology of connective tissue. (R. Perez-Tamayo, M. Rojkind, eds.), p. 76. New York: Marcel Dekker 1973Google Scholar
  3. Sainte-Marie, G.: A Paraffin embedding technique for studies empolying immunofluorescence. J. Histochem. Cytochem.10, 250–256 (1962)Google Scholar
  4. Skinner, M., Cohen, A.S.: Aspects of the Amyloid P-component. In: Amyloidosis. (O. Wegelius, A. Pasternak, eds.), p. 339. London-New York-San Francisco: Academic Press 1976Google Scholar
  5. Spark, E.L., Shirahama, T., Skinner, M., Cohen, A.S.: The identification of amyloid P-component (protein AP) in normal cultured human fibroblasts. Lab. Invest.38, 556–559 (1978)PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • H. -M. Schneider
    • 1
    • 2
  • M. Loos
    • 1
    • 2
  1. 1.Institute of PathologyUniversity of MainzFederal Republic of Germany
  2. 2.Institute of Medical MicrobiologyUniversity of MainzFederal Republic of Germany

Personalised recommendations