Virchows Archiv B

, Volume 54, Issue 1, pp 111–118 | Cite as

A semiautomatic image analyzing system based on an APPLE II or IIe personal computer

  • M. Oberholzer
  • H. Kuhn
  • H. Christen
  • R. Ettlin
  • H. Meyer
  • Ph. U. Heitz


A new semiautomatic image analyzing system based on an APPLE II or IIe personal computer is described. The configurations of the hardware and software are extensively explained. The possibilities of applying the system are demonstrated by different examples taken from various projects in biological research and clinical pathology. The system is desingned to fulfil the following requirements: (1) stepwise realization as a unit-by-unit system according to individual needs and interests, (2) acquisition and calculation of morphometric parameters, (3) provision of solutions for the greatest possible number of given problems in clinical and experimental pathology, (4) direct connection of the system to host computers for on-line data transfer and evaluation, and (5) optimum cost-benefit ratio by manifold application possibilities for the individual hardware and software elements. The advantages of the unit-by-unit system with personal computers outweigh in many respects the disadvantages (for example, increased file handling and limited capacity) in comparison with the closed automatized image evaluation system, particularly with regard to costs, flexibility and compatibility. The system is being further developed in collaboration with Kontron Bildanalyse GmbH, Eching/Munich, FRG.

Key words

Image analysis Data evaluation Data handling Morphometry Stereology Microcomputer APPLE II/IIe IBM personal computer 


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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • M. Oberholzer
    • 1
  • H. Kuhn
    • 2
  • H. Christen
    • 3
  • R. Ettlin
    • 4
  • H. Meyer
    • 5
  • Ph. U. Heitz
    • 1
  1. 1.Department of PathologyUniversity of BaselBasel
  2. 2.Biological-Pharmaceutical Research DepartmentF. Hoffmann-La Roche & Co. Ltd.Basel
  3. 3.Computer CenterUniversity of BaselBasel
  4. 4.Preclinical ResearchSandoz Ltd.Basel
  5. 5.GrasswilSwitzerland

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