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Folia Microbiologica

, Volume 25, Issue 6, pp 464–466 | Cite as

Production of rhodomycins inStreptomyces griseoruber 4620

  • M. Podojil
  • M. Blumauerová
  • V. Přikrylová
  • Z. Vaněk
  • G. F. Gauze
  • T. S. Maksimova
Article

Abstract

The strainStreptomyces griseoruber 4620 produces, besides the anthracycline antibiotics beromycins, some other anthracyclines of the rhodomycin type. Twelve isolates exhibiting a higher antibiotic activity (up to 2.5×), as compared to the parent strain, were obtained after a spontaneous selection. The following species were isolated from the hydrolysate of mycelial extract: β-rhodomycinone, β-isorhodomycinone, α2-rhodomycinone and 10-deoxy-β-rhodomycinone, which has not yet been described.

Keywords

Streptomyces Methanolic Extract Parent Strain Anthracyclines Submerged Cultivation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Academia, Publishing House of the Czechoslovak Academy of Sciences 1980

Authors and Affiliations

  • M. Podojil
    • 1
  • M. Blumauerová
    • 1
  • V. Přikrylová
    • 1
  • Z. Vaněk
    • 1
  • G. F. Gauze
    • 2
  • T. S. Maksimova
    • 2
  1. 1.Department of Molecular Biology and Genetics, Institute of MicrobiologyCzechoslovak Academy of SciencesPrague 4
  2. 2.Institute of New AntibioticsAcademy of Medical Sciences of the USSRMoscow

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