Folia Microbiologica

, 12:132 | Cite as

Synthesis of β-galactosidase inEscherichia coli in the presence of phenylalanine analogues

  • J. Janeček


The effect of phenylalanine analogues (p-F-phenylalanine, phenylserine and furylalanine) is described on the synthesis of inducible β-galactosidase inEscherichia coli ML-30 and phenylalanine requiring mutant ML-48. The incorporation of these analogues into the enzyme molecule results in the formation of a protein sensitive to a different extent to heat, urea and trypsin. The influence of the analogues on the ability to concentrate inducer inside the cells is also described. The different effect of the analogues on the synthesis and stability of the enzyme is discussed.


Phenylalanine Enzyme Molecule Grown Cell Natural Amino Acid Bacterial Extract 
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Copyright information

© Academia, nakladatelství Československé akademie věd 1967

Authors and Affiliations

  • J. Janeček
    • 1
  1. 1.Department of General Microbiology, Institute of MicrobiologyCzechoslovak Academy of SciencesPrague 4

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