Indian Journal of Clinical Biochemistry

, Volume 11, Issue 2, pp 148–151 | Cite as

Blood selenium levels of Indians: Delhi area

  • Jasvinder K. Gambhir
  • P. Lali
Trace Elements


Whole blood and plasma selenium levels were measured in 40 healthy Indian residents living in and around Delhi (20 males and 20 females). The mean whole blood and plasma selenium levels were 169.0±40 and 139.0±36.7 ng/ml in males and 161.2±46.2 and 128±40.6 ng/ml (mean±SD) in females, respectively. These blood levels did not differ significantly between males and females and are consistent with adequate selenium status. From regression plots based on the present results and literature data, it is expected that the probable mean selenium intake could be about 122 and 112 μg/day in males and females respectively.

Key words

Blood selenium plasma selenium selenium intake 


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  1. 1.
    Schwarz, K. and Foltz, C.M. (1975) Selenium as an integral part of factor 3 against dietary nectrotic liver degeneration. J. Am. Chem. Soc. 79, 3292–3293.CrossRefGoogle Scholar
  2. 2.
    Potruck, J.T., Pope, A.L., Ganther, H.E., Swanson, A.B., Hafeman, D.G. and Hoekstra, W.G. (1973) Selenium: biochemical role as a component of glutathione peroxidase. Science 179, 588–590.CrossRefGoogle Scholar
  3. 3.
    Chance, B., Sies, H. and Boveris, A. (1979) Hydroperoxides metabolism in mammalian organs. Physiol. Reviews. 59, 527–605.Google Scholar
  4. 4.
    Clark, L.C. (1985) The epidemiology of selenium and cancer. Fed. Proc. 44, 2584–2589.PubMedGoogle Scholar
  5. 5.
    Salonen, J.T., Alfthan, G., Huttunen, J.K., Pikkarainen, J. and Puska, P. (1982) Association between cardiovascular death and myocardial infarction and serum selenium in a matched pair longitudinal study. Lancet. 2, 175–179.PubMedCrossRefGoogle Scholar
  6. 6.
    Food and Nutritional Board, Recommended Dietary Allowances, 9th rev ed. Washington DC. National Academy of Sciences, 1980.Google Scholar
  7. 7.
    Cary, E.E., Allaway, W.H. and Miller, M. (1973) Utilization of different forms of dietary selenium. J. Anal. Sci. 36, 285–292.Google Scholar
  8. 8.
    Selenium: Environmental Health Criteria 58. World Health Organization, Geneva, 1987, 1–24.Google Scholar
  9. 9.
    Spallholz, J.E., Collins, G.E. and Schwarz, K. (1978) A single test tube method for the fluorometric microdetermination of selenium. Bioinorg. Chem. 9, 453–459.CrossRefGoogle Scholar
  10. 10.
    AOAC. Official methods of analysis, 12th ed. Washington DC, Association of Official Analytical Chemists, 1975.Google Scholar
  11. 11.
    Metabolism of Selenium in ‘Selenium: Environmental Health Criteria 58’, World Health Organization, Geneva, 1987, 67–90.Google Scholar
  12. 12.
    Krishnaswamy, K., Prasad, M.P.R., Krishna, T.P. and Pasricha, S. (1993) A case control study of selenium in cancer. Indian J. Med. Res. (B) 98, 124–128.Google Scholar
  13. 13.
    Yang, G.Q., Wang, S., Zhon, R. and Sun, S. (1983) Endemic selenium intoxication of hunans in China. Am. J. Clin. Nutr. 37, 872–881.PubMedGoogle Scholar
  14. 14.
    Rea, H.M., Thomson, C.D., Campbell, D.R. and Robinson, M.F. (1979) Relation between erythrocyte Se concentrations and glutathione peroxidase activities of New Zealand residents and visitors to New Zealand. Br. J. Nutr. 42, 201–208.PubMedCrossRefGoogle Scholar
  15. 15.
    Alfthan, G., Aro, A., Arvilommi, H. and Huttunen, J.K. (1991) Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite and selenate. Am. J. Clin. Nutr. 53, 120–125.PubMedGoogle Scholar
  16. 16.
    Tarp, U., Hansen, J.C., Overvad, K., Thorling, E.B., Tarp, B.D. and Graudal, H. (1987) Glutathione peroxidase activity in patients with rheumatoid arthritis and in normal subjects: effect of long term selenium supplementation. Arthritis Rheum. 30, 1162–1166.PubMedCrossRefGoogle Scholar
  17. 17.
    Allaway, W.H., Kubota, J., Losee, F. and Roth, M. (1968) Selenium, molybdenum and vanadium in human blood. Arch. Environ. Health. 16, 342–348.PubMedGoogle Scholar
  18. 18.
    Levander, O.A. (1976) Selenium in foods. In: Proceedings of the symposium on Selenium-Tellurium in the environment, Pittsburgh, Pennsylvania, Industrial Health Foundation. 26–53.Google Scholar
  19. 19.
    Thompson, J.N., Erdody, P. and Smith, D.C. (1975) Selenium content of food consumed by Canadians. J. Nutr. 105, 274–277.PubMedGoogle Scholar
  20. 20.
    Levander, O.A. (1985) Considerations on the assessment of selenium status. Federation Proc. 44, 2579–2583.Google Scholar
  21. 21.
    Keshan Disease Research Group (1979) Epidemiologic studies on the etiologic relationship of selenium and Keshan disease. Chin. Med. J. (Engl Ed) 92, 477–482.Google Scholar
  22. 22.
    Shamberger, R.J., Tytko, S.A. and Willis, C.E. (1976) Antioxidants and Cancer Part VI. Selenium and age-adjusted human cancer mortality. Arch. Environ. Health. 31, 231–235.PubMedGoogle Scholar

Copyright information

© Association of Clinical BIochemists of India 1996

Authors and Affiliations

  • Jasvinder K. Gambhir
    • 1
  • P. Lali
    • 1
  1. 1.Department of BiochemistryUniversity College of Medical Sciences & Guru Teg Bahadur HospitalDelhi

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