Degradation of 5′ adenosine monophosphate in a cell-free system ofEscherichia coli
- 26 Downloads
Sonicated cells ofEscherichia coli contain an enzyme system degrading 5′ adenosine monophosphate (5′ AMP) to hypoxanthine. This enzyme system is located in the fraction sedimenting at 20,000 xg. It has a pH optimum at 8.0. In the fraction sedimenting at 20,000 xg the enzyme activity was inhibited by adenosine triphosphate (ATP). Adenosine and adenine are deaminated by this enzyme preparation to inosine and to hypoxanthine, these activities not being inhibited by ATP.
KeywordsAdenosine Adenine Bran Enzyme Preparation Ribose
5′ adenosine monophosphate
- Ado-3′, 5′-P
cyclic 3′, 5′-adenosine monophosphate
Unable to display preview. Download preview PDF.
- Meijbaum, W. Z.:Über die Bestimmung kleiner Pentosemengen, insbesonders in Derivaten der Adenylsäure. Ztschr. Physiol. Chem. 258: 117, 1939.Google Scholar