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Stability of total and free prostate specific antigen in serum samples at different storage conditions

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Abstract

The present preliminary study was performed to find out stability of total prostate specific antigen (PSA) and free prostate specific antigen (FPSA) in serum of healthy males as well as in patients of benign and malignant disorders of prostate at various freezing and nonfreezing temperatures and at different duration of time.

The results of our study indicated long-term stability of both the analytes in frozen serum. Serum total and free PSA were stable only for three to four days in regular refrigerators in unfrozen states. Clotted blood kept at room temperature (25°C–30°C) did not cause change in concentrations of both the analytes for twenty four hours.

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Authors and Affiliations

  1. Department of Biochemistry, Nizam's Institute of Medical Sciences, Punjagutta, 500 082, Hyderabad, India

    G. Rajani Kumari & T. Malati

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  1. G. Rajani Kumari
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  2. T. Malati
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Correspondence to T. Malati.

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Kumari, G.R., Malati, T. Stability of total and free prostate specific antigen in serum samples at different storage conditions. Indian J Clin Biochem 19, 10–13 (2004). https://doi.org/10.1007/BF02894250

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