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Virchows Archiv B

, 9:153 | Cite as

Morphologische Veränderungen der Mäuse-Leber nach Inoculation von Arbo-Virus (typ Be An 67949)

  • F. Huth
  • R. de Araujo
Article
  • 8 Downloads

Morphologic changes of mouse-liver after inoculation of arbo-virus (type Be An 67949)

Summary

6–8 days post inoculation of Arbo-virus of type Be An 67949 differentiated virus particles with a medium size of 90 mμ can be observed in endothelial nuclei of newborn mice liver. The virus particles are characterized by double or single capsides and a dense round or polar center. Intranuclear virus reduplication is accompanied by strong proliferation of sinus lining cells and intensive necroses of liver parenchyma. In addition large intranuclear and varying intracytoplasmatic inclusion bodies are visible. The BeAn 67949 virus particles and the virogeneous hepatitis differ from those after inoculation of other virus and other virus hepatitis. The Be An 67949 virus induced hepatitis could be regarded as a model for a human virus hepatitis.

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Copyright information

© Springer-Verlag 1971

Authors and Affiliations

  • F. Huth
    • 1
  • R. de Araujo
    • 2
  1. 1.Institute de Patologia Regional der Universität Para/BrasilDeutschland
  2. 2.Pathologisches Institut der Universität DüsseldorfDeutschland

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