Pathology & Oncology Research

, Volume 2, Issue 1–2, pp 66–68 | Cite as

Total IgA and IgG in sera of patients with different primary malignancies

  • Terezija M Hrzenjak
  • Ante Roguljic
  • Palma Efenberger-Marinculic
  • Maja Popovic
  • Zoran Pisl
Short Communication


The concentrations of total serum IgA and IgG of 267 patients with different primary malignant tumors were measured by ELISA. Total serum IgA increased by 30% to 40% in patients with malignancies associated with mucous membranes (nasopharyngeal, gastrointestinal and bronchial carcinomas), while the change in total serum IgG was negligible. Although, the changes in Ig level could be influenced by many host factors, these data call attention to the potential indicative role of total serum IgA levels. Further studies are required to establish links between serum IgA levels and stages of tumor growth or tumor progression in order to use these values as prognostic factors.

Key words

IgA IgG malignant tumors 


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Copyright information

© Arányi Lajos Foundation 1996

Authors and Affiliations

  • Terezija M Hrzenjak
    • 1
  • Ante Roguljic
    • 2
  • Palma Efenberger-Marinculic
    • 3
  • Maja Popovic
    • 1
  • Zoran Pisl
    • 3
  1. 1.Department of Biology, Faculty of Veterinary MedicineUniversity of ZagrebZagrebCroatia
  2. 2.Clinic for Tumors and Allied DiseasesCroatia
  3. 3.Institute for Medical Research and Occupational HealthZagrebCroatia

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