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An ultrastructural study of spheroidal nuclear bodies found in gliomas

Eine elektronenoptische Untersuchung der spheroiden in den Gliomen gefundenen “nuclear bodies”

  • Published:
Virchows Archiv B

Zusammenfassung

Es wird berichtet über die Morphologie der „intranuclear bodies” in Gliomen des Menschen.

Das elektronenoptische Bild solcher „intranuclear bodies” variiert je nach dem Vorhandensein der unterscheidbaren strukturellen Komponenten. Danach lassen sich vier Typen differenzieren:

  1. Typ I.

    Kleine, fädige, von einer optisch leeren Zone umgebene “intranuclear bodies“.

  2. Typ II.

    Größer als Typ I mit einem granulären Kern, der konzentrisch von einer filamentösen Schicht umgeben ist.

  3. Typ III.

    “Intranuclear bodies” mit einem dichten granulären Kern und filamentös strukturierter umgebender Schicht.

  4. Typ IV.

    Größter “intranuclear body”, der alle drei Komponenten, Kern, granuläre und filamentöse Außenschicht enthält.

Summary

The morphology of intranuclear bodies observed in human gliomas, is described. The ultrastructural picture varies according to the number of structural components present in every intranuclear body. On this basis they are classified into four types:

  1. Type I.

    Small, filamentous intranuclear body, surrounded by a clear halo.

  2. Type II.

    Intranuclear body larger than type I, showing a filamentous periphery concentrically surrounding a granular center.

  3. Type III.

    Intranuclear body with a filamentous concentric layer around a granular core.

  4. Type IV.

    The largest intranuclear body showing the same three components: core, granular and filamentous layers.

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Authors and Affiliations

  1. Centro de Investigaciones Biologicas “Félix Huarte”, University of Navarra, Spain

    J. J. Vázquez, G. Ortuño & J. Cervós-Navarro

  2. Institute of Neuropathology, Klinikum Steglitz, Freie Universität Berlin, Germany

    J. J. Vázquez, G. Ortuño & J. Cervós-Navarro

Authors
  1. J. J. Vázquez
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  2. G. Ortuño
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  3. J. Cervós-Navarro
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Vázquez, J.J., Ortuño, G. & Cervós-Navarro, J. An ultrastructural study of spheroidal nuclear bodies found in gliomas. Virchows Arch. Abt. B Zellpath. 5, 288–293 (1970). https://doi.org/10.1007/BF02893570

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  • DOI: https://doi.org/10.1007/BF02893570

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