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Virchows Archiv B

, Volume 5, Issue 1, pp 288–293 | Cite as

An ultrastructural study of spheroidal nuclear bodies found in gliomas

  • J. J. Vázquez
  • G. Ortuño
  • J. Cervós-Navarro
Article

Summary

The morphology of intranuclear bodies observed in human gliomas, is described. The ultrastructural picture varies according to the number of structural components present in every intranuclear body. On this basis they are classified into four types:
  1. Type I.

    Small, filamentous intranuclear body, surrounded by a clear halo.

     
  2. Type II.

    Intranuclear body larger than type I, showing a filamentous periphery concentrically surrounding a granular center.

     
  3. Type III.

    Intranuclear body with a filamentous concentric layer around a granular core.

     
  4. Type IV.

    The largest intranuclear body showing the same three components: core, granular and filamentous layers.

     

Keywords

Central Core Oligodendroglioma Uranyl Acetate Rhein Nuclear Body 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Eine elektronenoptische Untersuchung der spheroiden in den Gliomen gefundenen “nuclear bodies”

Zusammenfassung

Es wird berichtet über die Morphologie der „intranuclear bodies” in Gliomen des Menschen.

Das elektronenoptische Bild solcher „intranuclear bodies” variiert je nach dem Vorhandensein der unterscheidbaren strukturellen Komponenten. Danach lassen sich vier Typen differenzieren:
  1. Typ I.

    Kleine, fädige, von einer optisch leeren Zone umgebene “intranuclear bodies“.

     
  2. Typ II.

    Größer als Typ I mit einem granulären Kern, der konzentrisch von einer filamentösen Schicht umgeben ist.

     
  3. Typ III.

    “Intranuclear bodies” mit einem dichten granulären Kern und filamentös strukturierter umgebender Schicht.

     
  4. Typ IV.

    Größter “intranuclear body”, der alle drei Komponenten, Kern, granuläre und filamentöse Außenschicht enthält.

     

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Copyright information

© Springer-Verlag 1970

Authors and Affiliations

  • J. J. Vázquez
    • 1
    • 2
  • G. Ortuño
    • 1
    • 2
  • J. Cervós-Navarro
    • 1
    • 2
  1. 1.Centro de Investigaciones Biologicas “Félix Huarte”University of NavarraSpain
  2. 2.Institute of Neuropathology, Klinikum SteglitzFreie Universität BerlinGermany

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