Virchows Archiv B

, Volume 7, Issue 1, pp 356–366 | Cite as

Banded structures in the connective tissue of lymphomas, lymphadenitis, and thymomas

  • F. Mollo
  • G. Monga


The fine structure of the connective tissue in forty-six pathological lymph nodes and in two granulomatous thymomas from human surgical material has been studied. Peculiar banded structures were extensively present in 20 cases of Hodgkin’s disease (out of 24 cases) and in the 2 granulomatous thymomas, while they have occasionally been observed in 2 reticulum cell sarcomas (out of 6 cases), in 4 lymphosarcomas (out of 7 cases), and in 1 lymphadenitis (out of 5 cases); they have not been recorded in chronic lymphoid (3 cases) or acute (1 case) leukaemias.

The significance of the banded structures and of other features (such as microfibrils, and patterns suggesting a fragmentation and dissociation of collagen fibres) has been discussed; their formal genesis and their relationships with processes of development and/or degradation of collagen fibres, and with the occurrence of hyaline changes, have been considered. The banded structures are regarded as a characteristic even though nonspecific feature in the electron microscopical picture of Hodgkin’s disease in lymph nodes.


Collagen Fibre Thymoma Lymphadenitis Dark Band Lymphosarcoma 
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Copyright information

© Springer-Verlag 1971

Authors and Affiliations

  • F. Mollo
    • 1
  • G. Monga
    • 1
  1. 1.Centro di Microscopia Elettronica della Facoltà di Medicina e ChirurgiaIstituto di Anatomia e Istologia Patologica (Cattedra II)TorinoItala

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