Adenomatoid tumor: Immunohistological features suggesting a mesothelial origin

  • Veli-Pekka Lehto
  • Markku Miettinen
  • Ismo Virtanen


Four adenomatoid tumors of the epididymis were evaluated immununohistologically for the expression of intermediate filaments and endothelial cell markers, factor VIII-related antigen and binding of Ulex europaeus I-lectin (UEA I). Immunofluorescence microscopy showed a strong reaction with antikeratin but not with anti-vimentin antibodies, indicating that adenomatoid tumor cells contain epithelial but not mesenchymal type of intermediate filaments. No staining of tumor cells was seen with anti-FVIII-related antigen antibodies or with fluorochrome-coupled UEA I. The results support the mesothelial, non-endothelial origin of adenomatoid tumors.

Key words

Adenomatoid tumor Epididymis Immunofluorescence Intermediate filaments Lectin 


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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • Veli-Pekka Lehto
    • 1
  • Markku Miettinen
    • 1
  • Ismo Virtanen
    • 1
  1. 1.Department of PathologyUniversity of HelsinkiHelsinki 29Finland

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