Virchows Archiv B

, Volume 22, Issue 1, pp 143–149 | Cite as

Ultrastructural changes in human leukemic cell nuclei

  • Alberto Conforti
  • Ludovico Medolago-Albani
  • Luciano Alessio


The ultrastructural changes of human leukemic cell nuclei have been investigated.

Particular attention is paid to the alteration of the nuclear envelope and its constituents, i.e., the pores and the Zonula Nucleum Limitans which appear constantly involved in these pathologic processes. An alteration of the relationships between the components of the nuclear envelope and the chromatin itself may be responsible for the appearance of the most nuclear changes.

Key words

Leukemia Nucleus Nuclear envelope 


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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • Alberto Conforti
    • 1
  • Ludovico Medolago-Albani
    • 1
  • Luciano Alessio
    • 1
  1. 1.Institute of General PathologyUniversity of RomeRomeItaly

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