Journal of Tongji Medical University

, Volume 11, Issue 4, pp 240–243 | Cite as

An Approach to the appropriate dosage of essential amino acids in the treatment of chronic renal failure

  • Xiao Hui-wen


110 cases of chronic renal failure (CRF) were randomly divided into two groups (I and II). No significant differences in renal function between the two groups were found before treatment. All patients were put on a low protein, low phosphorus and high caloric diet. Group I was treated with EAA in a routine dose while group II was given the same EAA in a much smaller dosage. The therapeutic effects observed in group II proved to be much better than in group I in almost all aspects surveyed (P< 0.001), including relief of symptoms, fall in Scr and BUN concentrations, favourable changes in amino acid profile, etc.

Key words

chronic renal failure essential amino acid 


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  1. 1.
    Giordano C, et al. Use of exogenous and endogenous urea for protein synthesis in uremic subjects. J Lab Clin Med 1963;62:231PubMedGoogle Scholar
  2. 2.
    Alvestrand A, et al. Clinical results of long term treatment with a low protein diet and a new amino acid preparation in patients with chronic uremia. Clin Nephrol 1983;19(2):67PubMedGoogle Scholar

Copyright information

© Springer 1991

Authors and Affiliations

  • Xiao Hui-wen
    • 1
  1. 1.Department of Internal Medicine, Tongji HospitalTongji Medical UniversityWuhan

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