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Journal of Tongji Medical University

, Volume 20, Issue 1, pp 20–22 | Cite as

Development of a surface acoustic wave LB membrane immunity sensor

  • Shen Jie
  • Shu Na
  • Ren Shu
  • Zhou Xianming
  • Zhou Xianming
Article

Summary

A new kind of biosensor for immunology was developed by ultrasonic technique and LB membrane. A double delay-line resonator was made by using ST-cut quartz crystal with working frequency of 149. 7 MHz. Then a layer of LB membrane was covered on it. When anti-IgM antibody of various concentrations was added to it, the sensor can be used to detect IgM antigen. The biosensor was highly sensitive, small and light. The experimental results showed that the working frequency change of the sensor was proportional to the concentration of antibody with its dilution ratio between 1: 10000 and 1: 100. It was also first observed that the frequency curve of the sensor resulting from the reaction of IgM antigen and antibody undulated in the experiment.

Key words

sensor immunology surface acoustic wave LB membrane 

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Copyright information

© Springer 2000

Authors and Affiliations

  • Shen Jie
    • 1
  • Shu Na
    • 1
  • Ren Shu
    • 1
  • Zhou Xianming
    • 1
  • Zhou Xianming
    • 2
  1. 1.Department of Biomedical Engineering, Center of Experimental MedicineTongji Medical UniversityWuhan
  2. 2.Research Institute of SonicsChinese Academy of SciencesBeijing

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