Folia Microbiologica

, Volume 23, Issue 6, pp 460–464 | Cite as

Inhibition of photo-inducedTrichoderma viride conidiation by inhibitors of RNA synthesis

  • V. Betina
  • J. Zajacová


The photo-induced conidiation ofTrichoderma viride is suppressed by ethidium bromide, acriflavin, lomofungin and 8-quinolinol at concentrations which do not inhibit the colony growth of this deuteromycete.


Ethidium Bromide Arginase Acridine Orange Colony Growth Allophanate 
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  1. Betina V., Spišiaková J.: Suppression of photo-induced sporulation inTrichoderma viride by inhibitors.Folia Microbiol. 21, 362 (1976).CrossRefGoogle Scholar
  2. Betina V., Zajacová J.: Regulation of periodicity and intensity of photoinduced conidiation in the fungusTrichoderma viride.Folia Microbiol. 23, 453 (1978).Google Scholar
  3. Bossinger J., Cooper T. G.: Molecular events associated with induction of arginase inSaccharomyces cerevisiae.J. Bacterial. 131, 163 (1977).Google Scholar
  4. Creanor J., May J. W., Mitchinson J. M.: The effects of 8-hydroxyquinoline on enzyme synthesis in the fission yeastSchizosaccharomyces pombe.Eur. J. Biochem. 60, 487 (1975).PubMedCrossRefGoogle Scholar
  5. Frazer S. S. R.: Turnover of polyadenylated messenger RNA in fission yeast.Eur. J. Biochem. 60, 477 (1975).CrossRefGoogle Scholar
  6. Galun E., Gressel J.: Morphogenesis inTrichoderma: suppression of photoinduction by 5-fluorouracil.Science 151, 696 (1966).PubMedCrossRefGoogle Scholar
  7. Gatti C., Houssier C., Frederiq E.: Interaction of ethidium bromide with ribosomes. Absorption, fluorescence, circular dichroism and sedimentation studies.Biochim. Biophys. Acta 476, 65 (1977).PubMedGoogle Scholar
  8. Girgenti A. J., Whitford T. W., Cory J. G.: Inhibition of transfer ribonucleic acid nucleotidyl transferase (EC from Ehrlich tumor cells by proflavine sulfate and ethidium bromide.Enzyme 21, 225 (1976).PubMedGoogle Scholar
  9. Gressel J., Galun E.: Effect of 5-fluorouracil on the soluble RNA ofTrichoderma.Biochem. Biophys. Res. Commun. 24, 162 (1966).PubMedCrossRefGoogle Scholar
  10. Kuo S. C., Cano F. R., Lampen J. O.: Lomofungin, an inhibitor of ribonucleic acid synthesis in yeast protoplasts: its effects on enzyme formation.Antimicrob. Agents Chemother. 3, 716 (1973).Google Scholar
  11. Lampen J. O., Kuo S. C., Cano F. R.: Control of synthesis and secretion of exoenzymes by yeast protoplast, p. 143 inJ. R. Villanueva, I. Garcia-Acha, A. Grascon, F. Uruburu (Eds.):Yeast, Mould and Plant Protoplasts. Academic Press, New York 1973.Google Scholar
  12. Lawther R. P., Phillips S. L., Cooper T. G.: Lomofungin inhibition of allophanate hydrolase inSaccgaromyces cerevisiae.Mol. Gen. Genet. 137, 89 (1975).PubMedCrossRefGoogle Scholar
  13. Lindenmayer A., Schoen H. F.: Selective effects of purine and pyrimidine analogues and of respiratory inhibitors on perithecial development and branching inSordaria.Plant. Physiol. 42, 1059 (1967).PubMedGoogle Scholar
  14. Mial S. H., Walker I. O.: Structural studies on ribosomes. I. The binding of proflavine toEscherichia coli ribosomes.Biochim. Biophys. Acta 145, 82 (1967).Google Scholar
  15. Miko M., Chance B.: Ethidium bromide as an uncoupler of oxidative phosphorylation.FEBS Letters 54, 347 (1975).PubMedCrossRefGoogle Scholar
  16. Morgan R. S., Rhoads D. G.: Binding of acridine orange to yeast ribosome.Biochim. Biophys. Acta 145, 82 (1967).Google Scholar
  17. Polak A.: Effect of 5-fluorocytosine on protein synthesis and amino acid pool inCandida albicans.Sabouraudia 12, 309 (1974).PubMedGoogle Scholar
  18. Polak A., Scholer H. J.: Fungistatic activity, uptake and incorporation of 5-fluorocytosine inCandida albicans as influenced by pyrimidines and purines. II. Studies on distribution and incorporation.Pathol. Microbiol. 39, 334 (1973).Google Scholar
  19. Razin A., Mager J.: Studies on the mechanism of the inhibitory effects of ethidium bromide on purine nucleotide metabolism.Israel J. Chem. 2, 5 (1964).Google Scholar
  20. Schoen H. F., Berech J.: Prevention of 5-fluorouracil caused growth inhibition inSordaria fimicola.Antimicrob. Agents Chemother. 11, 234 (1977).PubMedGoogle Scholar
  21. Tomchick R., Mandel H. G.: Biochemical effects of ethidium bromide in microorganisms.J. Gen. Microbiol. 36, 225 (1964).PubMedGoogle Scholar
  22. Tönnensen T., Friesen J. D.: Inhibitors of ribonucleic acid synthesis inSaccharomyces cerevisiae: decay rate of messenger ribonucleic acid.J. Bacteriol. 115, 889 (1973).Google Scholar
  23. Tsuboi M., Kondo K., Yanagishima N.: Inhibition of sporulation by ethidium bromide and its reversal by fermentable sugars inSaccharomyces cerevisiae.Arch. Microbiol. 99, 295 (1974).PubMedCrossRefGoogle Scholar
  24. Warinq M.: Ethidium and propidium, p. 141 inJ. W. Corcoran, F. E. Hahn (Eds.):Antibiotics, Vol. III, Mechanism of Action of Antimicrobial and Antitumor Agents. Springer-Verlag, Berlin—Heidelberg New York 1975.Google Scholar
  25. Wolfe A. D.: Quinacrine and other acridines, p. 203 inJ. W. Corcoran, F. E. Hahn (Eds.):Antibiotics, Vol. III, Mechanism of Action of Antimicrobial and Antitumor Agents. Springer-Verlag, Berlin—Heidelberg—New York 1975.Google Scholar

Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1978

Authors and Affiliations

  • V. Betina
    • 1
  • J. Zajacová
    • 1
  1. 1.Department of Technical Microbiology and Biochemistry, Faculty of ChemistrySlovak Technical UniversityBratislava

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