Folia Microbiologica

, Volume 36, Issue 5, pp 498–501 | Cite as

Contribution of silver ion resistance to the pathogenicity ofPseudomonas aeruginosa with special reference to burn wound sepsis

  • R. Vasishta
  • M. Saxena
  • S. Chhibber


The virulence of a silver-ion-resistant (AgR) clinical isolate ofPseudomonas aeruginosa and its silver-sensitive mutant (AgS) was compared in the murine burn-wound sepsis model. The AgR strain showed significantly higher colonization of burned skinvis-a-vis the AgS strain. The altered pathogenicity may in part be due to the decrease in capsular content and cell surface hydrophobicity, accompanying the loss of silver ion resistance. The AgR and AgS strains, however, did not exhibit quantitatively significant differences in the production of extracellular hemolysins and proteinases.


Cell Surface Hydrophobicity Silver Sulfadiazine Cadmium Sulfate Cell Surface Change Tube Dilution Method 
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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1991

Authors and Affiliations

  • R. Vasishta
    • 1
  • M. Saxena
    • 1
  • S. Chhibber
    • 1
  1. 1.Department of MicrobiologyPanjab UniversityChandigarhIndia

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