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Folia Microbiologica

, Volume 36, Issue 5, pp 447–450 | Cite as

Effect of dimethyl sulfoxide on lysine production by a mutant ofBacillus subtilis with low homoserine dehydrogenase activity

  • H. O. Kalcheva
  • V. O. Shanskaya
  • J. Smutny
  • S. S. Maluta
Papers

Abstract

SomeBacillus subtilis mutants with different levels of homoserine dehydrogenase were described. Strains that do not accumulate methionine have a high homoserine dehydrogenase activity. Low activity was detected in mutants where cell growth was completely inhibited by 0.7 mmol/L methionine. A low concentration of dimethyl sulfoxide had a stimulatory effect on lysine production by the methionine-sensitive mutant ofBacillus subtilis.

Keywords

Homoserine Aspartate Kinase Coryneform Bacterium Lysine Biosynthesis Lysine Production 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1991

Authors and Affiliations

  • H. O. Kalcheva
    • 1
  • V. O. Shanskaya
    • 1
  • J. Smutny
    • 2
  • S. S. Maluta
    • 1
  1. 1.Institute of Molecular Biology and GeneticsKievUSSR
  2. 2.Institute of Animal PhysiologyKošiceCzechoslovakia

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